Vitamin A

Vitamin A

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1.What is Vitamin A?

Vitamin A (vitamin A), also known as retinol (the aldehyde derivative retinal) or anti-dry eye factor, is an unsaturated monohydric alcohol with an alicyclic ring. It is a kind of substance with retinol biological activity and belongs to fat. Soluble vitamins.


Natural vitamin A is extracted from cod liver oil. Among them, the fish liver is extracted from retinol (vitamin A1), and the freshwater fish liver is extracted from 3-dehydroretinol, vitamin A2.

Vitamin A is a fat-soluble vitamin that also acts as a powerful antioxidant in the body. It plays a critical role in maintaining vision, neurological function, healthy skin and more. Like all antioxidants, it’s also involved in reducing inflammation through fighting free radical damage.

Vitamin A is found in two primary forms: active vitamin A (also called retinol, which results in retinyl esters) andbeta-carotene. Retinol comes from animal-derived foods and is a type of “pre-formed” vitamin A that can be used directly by the body. The other type, which is obtained from colorful fruits and vegetables, is in the form of provitamin carotenoids. Beta-carotene and other types of carotenoids found in plant-based products need to first be converted to retinol, the active form of vitamin A, in order to be utilized by the body. Another form of vitamin A is palmitate, which usually comes in capsule form.


So what is vitamin A good for?


Studies have repeatedly shown that antioxidants like vitamin A are vital to good health and longevity. They benefit eye health, boost immunity and foster cell growth. Nutrition experts and physicians recommend obtaining antioxidants primarily by eating a well-balanced diet high in fruits, vegetables and whole foods whenever possible rather than from vitamin supplementation to maximize the potential health benefits.


Vitamin A is a component of rhodopsin that forms a weak light in visual cells. Rhodopsin is composed of opsin and 11-cis-retinal, which is related to dark vision.


The physiological function of vitamin A is to maintain the vision of the eye in the dark; to maintain the normal structure of the epithelial tissue; to promote growth and development. Vitamin A deficiency can cause dry eye, night blindness, epithelial hyperplasia and other symptoms.


2. Two Types of Vitamin A Additives: Vitamin A acetate & palmitate

The pure compound of vitamin A is retinol, which is easily destroyed. Thus, the first step in making a vitamin A additive is to esterify it first. “Esterification” is beneficial to the stability of vitamin A additives. The organic acids that esterify vitamin A are commonly used in acetic acid, propionic acid and palmitic acid.


The melting point of vitamin A acetate is 57.3-58.4 ° C, and the melting point of vitamin A palmitate is 27.8-28.9 ° C. Both UV and oxygen can cause the breakdown of vitamin A acetate and vitamin A palmitate.


Vitamin A acetate fat-soluble is an essential factor regulating the growth and health of epithelial cells, which makes the surface of rough aging skin thinner, promotes the normalization of cell metabolism, and has obvious wrinkle effect. Can be used in skin care, wrinkle, whitening and other advanced. Light yellow crystal; easy to oxidize in air, easily deteriorated when exposed to light, slightly soluble in ethanol, insoluble in water.


Vitamin A palmitate combined with neuromuscular blockers, central anesthetics, opioid analgesics with respiratory depression, can strengthen neuromuscular blockade and respiratory depression; combined with anti-muscle drugs can make anti-muscle The effect of muscle relaxation is weakened. Do not use with chlorotoxin and erythromycin. In combination with gentamicin and colistin, the antibacterial effect of the drug may be enhanced. It is a drug.


Even if it is esterified, vitamin A is more likely to be destroyed. Therefore, fine particles can be further formed by microcapsule technology, adsorption method, emulsification process, etc., and can be dispersed in water, and can be mixed with drinking water as feed.

Vitamin A additives have different particle sizes due to different process conditions. Although the regulation is generally between 0.1 and 1.0 mm, it is actually more than 0.177 to 0.590 mm. Vitamin A additive that can be dispersed in water, with a smaller particle size, up to a maximum of 0.35 mm.

3. Specifications of Vitamin A




Pale yellow to yellow flowing powder

Loss on drying


Vitamin A palmitate /Acetate Content



Fat-soluble Alcohol


100% go through the sieve of 0.84mm
(US standard mesh sieve No.20)

Heavy metal










Total plate count


Yeast &mold



≤0.3 MPN/g


Negative /10g


Negative /25g


Store in the original container, protected from light, in a dry, cool 8-15oC) place.



4.Functions & Health Benefits of Vitamin A

Vitamin A is essential for a healthy body and it has many beneficial properties, including those listed below.

  1. Protects Eye Health
  2. Supports Immunity
  3. Relieves Inflammation
  4. Skincare:Keeps Skin Glowing
  5. Contains Cancer-Fighting Properties
  6. Boosts Bone Health
  7. Reduces Cholesterol
  8. Aids in Reproduction and Development
  9. Promotes Tissue Repair
  10. Prevents Urinary Stones
  11. Industries: Cometics, Feed, Pharmaceuticals etc

1.Protects Eye Health

One of the most well-known benefits of vitamin A is its ability to boost vision and keep your eyes healthy. This is because it is a critical component of the rhodopsin molecule, which is activated when light shines on the retina, sending a signal to the brain that results in vision. Beta-carotene plays a role in preventing macular degeneration, one of the leading causes of age-related blindness.

2.Supports Immunity

Vitamin A plays an integral role in immune health and may be especially beneficial for warding off illness and infections. According to a review out of Baltimore, a deficiency in this key vitamin can weaken immunity and even alter the function of immune cells.


3.Relieves Inflammation

Beta-carotene acts as a powerful antioxidant in the body, helping reduce the buildup of harmful free radicals and prevent oxidative damage to cells while also blocking inflammation.


4.Keeps Skin Glowing

Often prescribed by dermatologists to fight acne and wrinkles alike, vitamin A is revered for its potent skin-enhancing properties.Due to its anti-inflammatory properties, such as retinaldehyde, vitamin A may also be useful in the treatment of a wide range of skin concerns.


5.Contains Cancer-Fighting Properties

Vitamin A is a powerful antioxidant, which can prevent certain forms of cancer. Natural and synthetic retinoids have been used as potential chemotherapeutic or chemopreventive agents because of their differentiation, antiproliferative, proapoptotic, and antioxidant effects.


6.Boosts Bone Health

Vitamin A helps in the formation of dentin, a layer of hard material just below the surface of the teeth, thereby enhancing its strength.


7.Reduces Cholesterol

Getting enough vitamin A in your diet may help naturally lower cholesterol levels to optimize heart health. An animal model out of Brazil, for instance, found that supplementing rats with beta-carotene for six weeks was able to significantly slash levels of total cholesterol in the blood.


8.Aids in Reproduction and Development

Vitamin A as one of the most important micronutrients during pregnancy, especially with regard to lung function and maturation. Beta-carotene is also considered critical in the prevention of developmental disorders for women who are pregnant or breastfeeding.

9.Promotes Tissue Repair

When it comes to tissue repair and cell regeneration, getting enough vitamin A in your diet is key. Besides being vital to promoting proper skin health, some evidence even suggests that this vitamin could aid in wound healing as well.


10.Prevents Urinary Stones

Some research shows that vitamin A may aid in the prevention of urinary stones. In fact, one study out of the National Institute of Nutrition’s Department of Biophysics in India examined the relationship between vitamin A levels and urinary stone formation among children and found that those with low levels of vitamin A had greater levels of calcium oxalate crystals in the urine, indicating a higher risk of urinary stone formation.

11.Industries: Cometics, Feed, Pharmaceuticals etc

  • Skin care Beauty industry: used in eye creams, moisturizers, repair creams, shampoos, conditioners, etc.
    1. It has the effect of regulating the metabolism of the epidermis and the stratum corneum, and can resist aging and wrinkle.
    2. It can reduce the sebum overflow and make the skin elastic, while dilute the spots and soften the skin.
    3. Helps protect the epidermis, the mucous membrane is not affected by bacteria, healthy skin, and prevent skin cancer.
    4. Effectively prevent obesity and maintain a slim figure for women.
    5. Can help prevent hair loss

  • Feed industry:
    Products: Vitamin A Acetate, Vitamin A Palmitate.
    Character: Unstable nature, anti-oxidant and stabilizer should be added as auxiliary materials to make particles and should be stored in the dark.
  • Pharmaceutical industry:
    1. Prevention of night blindness, vision loss, treatment of various eye diseases, so that women are clear and good.
    2. Vitamin A can treat dry eye, corneal softening, dry skin and night blindness. In addition, it is also effective for hot, frostbite and ulcers (peptic ulcers, stress ulcers).

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