1. Introduction

Rutin is a powerful flavonoid antioxidant extracted from Sophora japonica L. (Japanese pagoda tree). It is widely used in pharmaceuticals, dietary supplements, cosmetics, and food formulations for its vascular-protective, anti-inflammatory, and antioxidant properties.

Chibio Biotech offers two grades of high-purity Rutin:
✅ Rutin NF11 – Standard-grade rutin commonly used in supplements & pharmaceuticals.
✅ Rutin DAB10 – A refined version with higher purity and lower impurities, suitable for premium formulations.

Rutin – Chemical Information

• CAS Number: 153-18-4
• Molecular Formula: C27H30O16
• Molecular Weight: 610.52 g/mol
• Solubility:
  ✔ Water – Slightly soluble (0.125 g/L at 20°C)
  ✔ Ethanol – Sparingly soluble
  ✔ Methanol – Soluble
  ✔ Alkali Hydroxide Solutions – Soluble
  ✔ Chloroform, Ether, Benzene – Insoluble
• 📌 Key Properties:
  ✔ Flavonoid Glycoside – Composed of quercetin & rutinose sugar moiety.
  ✔ Low Water Solubility – Better dissolved in alkali solutions or alcohols.
  ✔ Stable at Room Temperature – Long shelf life if stored in dry, cool conditions.

2. Types of Rutin & Their Applications

📌 Key Features:
✔ High Purity (≥95% to 99%) – Meets pharmaceutical standards.
✔ Powerful Antioxidant & Vascular Support – Strengthens capillaries, reduces inflammation, and enhances circulation.
✔ Two Grades for Different Applications – NF11 (standard) & DAB10 (premium, refined version).

3. Comparison of Rutin NF11 vs. Rutin DAB10

📌 Which Type to Choose?

• For Standard Supplements & Cardiovascular Health → Rutin NF11
• For High-End Pharmaceuticals & Skincare → Rutin DAB10

4. Key Benefits of Rutin

🩸 Supports Vascular & Heart Health – Strengthens blood vessels & capillaries, reducing varicose veins & bruising.
🛡 Powerful Antioxidant & Anti-Inflammatory – Protects against oxidative stress & aging.
⚡ Enhances Circulation & Blood Flow – Prevents blood clots and improves vein elasticity.
🧴 Promotes Skin Health & UV Protection – Used in cosmetics for anti-aging & sun damage repair.
🦴 Supports Joint & Bone Health – Helps reduce arthritis-related inflammation.

5. Applications of Rutin

6. Production Flowchart for Rutin

📌 Step-by-Step Manufacturing Process

1️⃣ Rutin NF11 Production (Standard Grade)

1. Extraction from Sophora japonica L. – The plant material is crushed and infiltrated with solvent.
2. Precipitation & Filtration – Removing unwanted impurities.
3. Crystallization & Drying – Producing a stable rutin powder.
4. Final Processing & Packaging – Ensuring purity and compliance with NF11 standards​.

2️⃣ Rutin DAB10 Production (Refined, High-Purity Grade)

1. Starting Material: Rutin NF11 – NF11-grade rutin undergoes further purification.
2. Dissolution & Decolorization – Removing impurities and unwanted pigments.
3. Filtration & Concentration – Concentrating rutin for higher purity.
4. Crystallization & Drying – Producing a highly refined, pharmaceutical-grade Rutin DAB10.
5. Final Quality Control & Packaging – Ensuring compliance with DAB10 standards​.

7. Why Choose Chibio Biotech?

✔ High-Purity Rutin (95% – 99%) – NF11 & DAB10 grades available.
✔ Two Grades for Different Markets – Standard (NF11) & Premium (DAB10, refined).
✔  ISO Certified Production – Meeting global pharmaceutical & food safety standards.
✔ Vegan, Non-GMO, & Allergen-Free – Safe for all consumer segments.
✔ Bulk Supply & Private Labeling – Available for customized formulations & packaging.

8. Why Should Your Business Use Rutin?

🚀 High-Demand Ingredient in Vascular Health – Used for cardiovascular & vein support supplements.
💎 Clinically Researched Bioflavonoid – Extensively studied for blood circulation & antioxidant benefits.
💰 Versatile in Supplements, Pharmaceuticals & Skincare – Ideal for tablets, creams, and nutraceuticals.
🌍 Premium & Cost-Effective Options – NF11 for mass-market & DAB10 for high-end formulations.

📩 Get in Touch for Premium Rutin!

Looking for high-quality Rutin NF11 or DAB10 for supplements, pharmaceuticals, or skincare applications? 🌿

📧 Email: sales@chibiotech.com
📞 Phone: +86 (0)532 66983270
🌍 Website: www.chibiotech.com
✅ Enhance vascular health, skincare, and antioxidant protection with Chibio Biotech’s premium Rutin! 🚀