Vitamin B3 (Niacinamide / Nicotinamide)

Vitamin B3 (Niacinamide / Nicotinamide)

Category

Additional information

Product Name

Vitamin B3 (Niacinamide / Nicotinamide)

CAS No.

98-92-0

Form

White crystalline powder

Purity

≥99.5%

Solubility

Freely soluble in water and ethanol

Key Properties

✔️ Stable, odorless, neutral-tasting powder
✔️ Excellent aqueous solubility
✔️ Non-flushing alternative to nicotinic acid
✔️ Heat- and pH-stable for oral or topical use

Benefits

✅ Promotes Cellular Energy
✅ Brightens & Balances Skin
✅ Anti-Inflammatory & Anti-Acne
✅ Supports Nervous System & Cognitive Health
✅ Protects DNA & Promotes Detox

Main Applications

💊 Dietary Supplements
💧 Skincare & Dermocosmetics
🥣 Fortified Foods & Beverages
🐄 Animal Feed

Product Details

✅ Vitamin B3 (Niacinamide / Nicotinamide) – Non-Flushing B3 for Skin Clarity, Energy & Cellular Health

High-purity Vitamin B3 (≥99.5%) in its amide form—ideal for cosmetics, dietary supplements, and energy-boosting wellness formulations.


🌿 Product Overview

Niacinamide, also known as Nicotinamide, is the non-flushing form of Vitamin B3. It supports cellular energy, skin barrier repair, anti-inflammation, and coenzyme NAD⁺/NADP⁺ synthesis. Chibio Biotech provides USP, BP, EP, and food-grade niacinamide, widely used in skincare, nutrition, food fortification, and pharmaceutical applications.


🔍 Basic Information

Item Description
Product Name Niacinamide / Nicotinamide (Vitamin B3)
CAS No. 98-92-0
Molecular Formula C₆H₆N₂O
Molecular Weight 122.12 g/mol
Form White crystalline powder
Purity ≥99.5%
Solubility Freely soluble in water and ethanol
Shelf Life 36 months
Storage Store in a cool, sealed, and light-protected container
Grades Available USP Grade​, BP Grade​, Food Grade​

🧪 Specification Summary

Parameter USP/BP Grade Result
Assay 98.5%–101.5% 100.1%
Melting Point 128–131°C 128.7°C
pH (5% solution) 6.0–7.5 7.0
Loss on Drying ≤0.5% 0.1%
Heavy Metals ≤0.003% Complies

💧 Physicochemical Properties

  • ✔️ Stable, odorless, neutral-tasting powder

  • ✔️ Excellent aqueous solubility

  • ✔️ Non-flushing alternative to nicotinic acid

  • ✔️ Heat- and pH-stable for oral or topical use


🎯 Health & Cosmetic Benefits

Promotes Cellular Energy
Key precursor to NAD⁺ and NADP⁺ coenzymes involved in ATP synthesis.

Brightens & Balances Skin
Reduces hyperpigmentation, sebum overproduction, and redness.

Anti-Inflammatory & Anti-Acne
Used in skincare for rosacea, acne, and sensitive skin.

Supports Nervous System & Cognitive Health
Vital for neurotransmitter synthesis and neuroprotection.

Protects DNA & Promotes Detox
Enhances cellular repair and oxidative stress resistance.


🌐 Applications & Dosage

💊 Dietary Supplements

  • Form: Capsules, tablets, powder blends

  • Dosage: 100–500 mg/day

  • Function: Energy, cognition, NAD+ boosting

💧 Skincare & Dermocosmetics

  • Form: Creams, serums, toners, masks

  • Usage Level: 2–10%

  • Effect: Fades spots, improves elasticity, reduces oiliness

🥣 Fortified Foods & Beverages

  • Use: Energy bars, meal replacements, infant formula

  • Dosage: 5–20 mg/serving

  • Form: Water-soluble vitamin blend

🐄 Animal Feed

  • Use: Poultry, ruminant growth enhancer

  • Form: Premix powder or granules


🔄 Niacinamide Production Flowchart

Synthesis of Nicotinic Acid
→ Amidation with ammonia to yield Nicotinamide

Crystallization & Purification
→ Recrystallization to remove impurities

Drying & Sieving
→ Controlled drying and particle sizing

Quality Control
→ Assay, heavy metals, microbial limit, solubility

Packaging
→ Packed in double-layered light-protective drums


💼 Why Choose Chibio Biotech?

✅ Multi-Grade Selection

USP, BP, and food-grade options for every industry

🌱 Clean & Safe

Non-GMO, vegan, non-flushing, allergen-free

📊 Full Traceability

COA, MSDS, and technical support for all shipments

📦 Global Distribution Ready

OEM/private label, export documentation, and bulk logistics


💡 Why Use Niacinamide / Nicotinamide in Business?

Chibio’s Vitamin B3 (Niacinamide) empowers formulations across beauty and wellness sectors:

  • Clear, calm, and bright skin in topical skincare

  • Sustained energy metabolism without niacin flushing

  • Functional food and beverage fortification

  • Compliant with clean-label, vegan, and gluten-free markets

✅ Whether you’re building beauty-from-within supplements or anti-acne skincare—Chibio’s Niacinamide brings clinical results and market trust.


📊 Vitamin B3 Comparison Table: Niacin vs. Niacinamide

Feature Niacin (Nicotinic Acid) Niacinamide (Nicotinamide)
Chemical Name Nicotinic Acid Nicotinamide
CAS No. 59-67-6 98-92-0
Molecular Formula C₆H₅NO₂ C₆H₆N₂O
Solubility Sparingly soluble in cold water, more in hot Freely soluble in water & ethanol
Taste & Stability Slight bitterness; heat stable Neutral taste; highly stable
Metabolism Function Precursor to NAD⁺/NADP⁺ Also precursor to NAD⁺/NADP⁺
Flush Reaction Yes – causes vasodilation and skin flushing No flushing effect
Cholesterol Impact Reduces LDL & triglycerides; increases HDL No significant lipid-modulating effect
Skin Benefits Less used in cosmetics Excellent for brightening, anti-acne, and anti-aging
Dosage – Supplements 100–500 mg/day (max 2,000 mg in lipid control) 100–500 mg/day standard; up to 1,000 mg/day for skin/cognition
Topical Use Rarely used Widely used (2–10% in serums/creams)
Applications Cardiovascular supplements, detox, lipid support Skin care, NAD+ boosters, wellness supplements
Therapeutic Use Hyperlipidemia, circulation, detox protocols Acne, pigmentation, cognition, mental clarity
Irritation Potential Can cause flushing, tingling, itching Generally well-tolerated
Form Options Powder, tablet, slow-release Powder, capsule, cream, serum

✅ Summary Recommendations

  • Choose Niacin (Nicotinic Acid) if your product is focused on:

    • Lipid modulation (cholesterol, triglycerides)

    • Detoxification and blood flow enhancement

    • Medical-grade cardiovascular formulations

  • Choose Niacinamide (Nicotinamide) if your product is designed for:

    • Skin brightening, acne control, or anti-aging formulas

    • NAD+ cellular energy boosting

    • Non-flushing vitamin B3 supplementation


📌 Coenzyme Impact: Both Convert to NAD⁺

Despite different metabolic paths and uses, both forms ultimately contribute to NAD⁺ and NADP⁺ formation, essential for energy metabolism, DNA repair, and anti-aging processes.


📩 Request Free Sample or Quotation Now!

Looking for premium-grade Niacinamide (Vitamin B3) for your cosmetic, supplement, or functional food brand?

📧 Email: sales@chibiotech.com
📞 Phone: +86 (0)532 66983270
🌐 Website: www.chibiotech.com

Chibio Biotech – Scientifically Pure, Formulator-Trusted Vitamin B3

Get in touch with us to boost your business

Headquarter

Block B, Vanke Center, No.2 Heilongjiang South Road, Shibei District, Qingdao City, China 266033

Phone

+86 (0)532 66983270

Cellphone / WhatsApp / WeChat

+86 156 6577 2296
+86 133 8100 5417

sales@chibiotech.com

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