Vitamin B3 Niacin / Nicotinic Acid

Vitamin B3 Niacin / Nicotinic Acid

Category

Additional information

Product Name

Vitamin B3 Niacin / Nicotinic Acid

Cas No.

59-67-6

Form

White crystalline powder

Solubility

Sparingly soluble in water; soluble in boiling water and ethanol

Key Properties

✔️ Heat-stable, light-stable in dry form
✔️ Slightly bitter taste
✔️ Compatible with dry blends, capsules, tablets
✔️ Reacts synergistically with other B vitamins

Key Benefits

✅ Cellular Energy & Metabolism
✅ Cholesterol & Lipid Management
✅ Nervous System & Cognitive Health
✅ Skin Health & Repair
✅ Vascular Support
✅ Detoxification & DNA Repair

Main Applications

💊 Nutraceuticals & Clinical Supplements
🥣 Food & Beverage Fortification
🐄 Veterinary & Feed Use

Product Details

✅ Vitamin B3 (Niacin / Nicotinic Acid) – Essential for Energy Metabolism, Skin Health & Cholesterol Support

High-purity (≥99.5%) water-soluble B-vitamin used in nutritional supplements, functional food, and therapeutic formulations.


🌿 Product Overview

Vitamin B3, known as Niacin or Nicotinic Acid, is a water-soluble essential nutrient involved in cellular energy production (NAD/NADP), DNA repair, lipid regulation, and skin barrier function. Chibio’s Niacin is produced to meet USP2022 / EP10.0 standards, offering food-grade quality with ≥99.5% purity, suitable for dietary, therapeutic, and metabolic-support applications.


🔍 Basic Information

Item Description
Product Name Vitamin B3 (Niacin / Nicotinic Acid)
CAS No. 59-67-6
Molecular Formula C₆H₅NO₂
Molecular Weight 123.11 g/mol
Form White crystalline powder
Solubility Sparingly soluble in water; soluble in boiling water and ethanol
Storage <25°C, tightly sealed, dry conditions
Shelf Life 24 months
Standards USP2022 / EP10.0​

🧪 Specification (Based on COA)​

Parameter Specification Result
Appearance White crystalline powder Complies
Odor Slight characteristic odor Complies
Solubility Water and ethanol soluble Complies
Identification (A–D) IR, UV, Color, HPLC Complies
Assay 99.5% – 101.0% 100.32%
Melting Point 234–238°C 236.5°C
Chloride ≤0.02% <0.02%
Sulfate ≤0.02% <0.02%
Loss on Drying ≤1.0% 0.27%
Residue on Ignition ≤0.1% 0.00%
Related Compounds USP standard Complies

💧 Physicochemical Properties

  • ✔️ Heat-stable, light-stable in dry form

  • ✔️ Slightly bitter taste

  • ✔️ Compatible with dry blends, capsules, tablets

  • ✔️ Reacts synergistically with other B vitamins


🎯 Health Benefits of Vitamin B3

Cellular Energy & Metabolism
Functions as a precursor for coenzymes NAD⁺ and NADP⁺, essential for energy production.

Cholesterol & Lipid Management
Clinically shown to reduce LDL and triglycerides while boosting HDL levels.

Nervous System & Cognitive Health
Supports brain function, neurotransmitter synthesis, and may help prevent age-related decline.

Skin Health & Repair
Promotes healthy skin barrier and is used in treating pellagra (B3 deficiency).

Vascular Support
Improves circulation and reduces oxidative stress in capillary walls.

Detoxification & DNA Repair
Enhances phase I/II detox pathways and protects DNA from damage.


🌐 Applications & Dosage Forms

💊 Nutraceuticals & Clinical Supplements

  • Use: Energy, lipid control, cognitive and skin support

  • Dosage: 100–1,000 mg/day for therapeutic uses

  • Form: Capsules, tablets, time-release formulations

🥣 Food & Beverage Fortification

  • Use: Functional drinks, energy foods, cereals

  • Dosage: 5–20 mg/serving

  • Form: Granular, premix or solution-phase systems

🐄 Veterinary & Feed Use

  • Use: Nutrient premix for metabolic regulation in livestock

  • Dosage: Species-specific formulations for poultry, cattle, aquaculture


🔄 Niacin Production Flowchart

Chemical Synthesis
→ Oxidation of 3-methylpyridine or 3-cyanopyridine to nicotinic acid

Crystallization & Purification
→ Filtration, recrystallization for USP/EP-grade material

Drying & Milling
→ Low-temperature dehydration and micronization

QC Testing
→ Assay (HPLC), melting point, drying loss, related compounds

Packaging
→ Light-blocking drums or bags under controlled conditions


💼 Why Choose Chibio Biotech?

🧪 Multi-Standard Compliance

Meets USP2022, EP10.0 – validated for food, pharma, and feed

📊 Reliable Purity ≥99.5%

Each batch independently tested and verified with COA

🌱 Clean-Label Compatible

Vegan, non-GMO, gluten-free, and allergen-free

📦 Full-Service Supply

Bulk, private label, and formulation support available


💡 Why Use Vitamin B3 (Niacin) in Business?

Chibio’s Niacin provides businesses with a powerful, science-backed ingredient for:

  • Energy and endurance-focused nutrition

  • Cholesterol and vascular health formulas

  • Cognitive, skin, and cellular anti-aging products

  • Global-standard compliance for fortified food and pharma

✅ Whether you’re launching supplements, functional drinks, or wellness capsules, Chibio’s Vitamin B3 ensures efficacy, purity, and customer satisfaction.


📊 Vitamin B3 Comparison Table: Niacin vs. Niacinamide

Feature Niacin (Nicotinic Acid) Niacinamide (Nicotinamide)
Chemical Name Nicotinic Acid Nicotinamide
CAS No. 59-67-6 98-92-0
Molecular Formula C₆H₅NO₂ C₆H₆N₂O
Solubility Sparingly soluble in cold water, more in hot Freely soluble in water & ethanol
Taste & Stability Slight bitterness; heat stable Neutral taste; highly stable
Metabolism Function Precursor to NAD⁺/NADP⁺ Also precursor to NAD⁺/NADP⁺
Flush Reaction Yes – causes vasodilation and skin flushing No flushing effect
Cholesterol Impact Reduces LDL & triglycerides; increases HDL No significant lipid-modulating effect
Skin Benefits Less used in cosmetics Excellent for brightening, anti-acne, and anti-aging
Dosage – Supplements 100–500 mg/day (max 2,000 mg in lipid control) 100–500 mg/day standard; up to 1,000 mg/day for skin/cognition
Topical Use Rarely used Widely used (2–10% in serums/creams)
Applications Cardiovascular supplements, detox, lipid support Skin care, NAD+ boosters, wellness supplements
Therapeutic Use Hyperlipidemia, circulation, detox protocols Acne, pigmentation, cognition, mental clarity
Irritation Potential Can cause flushing, tingling, itching Generally well-tolerated
Form Options Powder, tablet, slow-release Powder, capsule, cream, serum

✅ Summary Recommendations

  • Choose Niacin (Nicotinic Acid) if your product is focused on:

    • Lipid modulation (cholesterol, triglycerides)

    • Detoxification and blood flow enhancement

    • Medical-grade cardiovascular formulations

  • Choose Niacinamide (Nicotinamide) if your product is designed for:

    • Skin brightening, acne control, or anti-aging formulas

    • NAD+ cellular energy boosting

    • Non-flushing vitamin B3 supplementation


📌 Coenzyme Impact: Both Convert to NAD⁺

Despite different metabolic paths and uses, both forms ultimately contribute to NAD⁺ and NADP⁺ formation, essential for energy metabolism, DNA repair, and anti-aging processes.


📩 Request Free Sample or Quotation Now!

Looking for premium-grade Vitamin B3 (Niacin / Nicotinic Acid) for your nutritional or therapeutic product?

📧 Email: sales@chibiotech.com
📞 Phone: +86 (0)532 66983270
🌐 Website: www.chibiotech.com

Chibio Biotech – Metabolic Wellness Starts with Precision Nutrition

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