Product Name | Vitamin B3 Niacin / Nicotinic Acid |
---|---|
Cas No. | 59-67-6 |
Form | White crystalline powder |
Solubility | Sparingly soluble in water; soluble in boiling water and ethanol |
Key Properties | ✔️ Heat-stable, light-stable in dry form |
Key Benefits | ✅ Cellular Energy & Metabolism |
Main Applications | 💊 Nutraceuticals & Clinical Supplements |
High-purity (≥99.5%) water-soluble B-vitamin used in nutritional supplements, functional food, and therapeutic formulations.
Vitamin B3, known as Niacin or Nicotinic Acid, is a water-soluble essential nutrient involved in cellular energy production (NAD/NADP), DNA repair, lipid regulation, and skin barrier function. Chibio’s Niacin is produced to meet USP2022 / EP10.0 standards, offering food-grade quality with ≥99.5% purity, suitable for dietary, therapeutic, and metabolic-support applications.
Item | Description |
---|---|
Product Name | Vitamin B3 (Niacin / Nicotinic Acid) |
CAS No. | 59-67-6 |
Molecular Formula | C₆H₅NO₂ |
Molecular Weight | 123.11 g/mol |
Form | White crystalline powder |
Solubility | Sparingly soluble in water; soluble in boiling water and ethanol |
Storage | <25°C, tightly sealed, dry conditions |
Shelf Life | 24 months |
Standards | USP2022 / EP10.0 |
Parameter | Specification | Result |
---|---|---|
Appearance | White crystalline powder | Complies |
Odor | Slight characteristic odor | Complies |
Solubility | Water and ethanol soluble | Complies |
Identification (A–D) | IR, UV, Color, HPLC | Complies |
Assay | 99.5% – 101.0% | 100.32% |
Melting Point | 234–238°C | 236.5°C |
Chloride | ≤0.02% | <0.02% |
Sulfate | ≤0.02% | <0.02% |
Loss on Drying | ≤1.0% | 0.27% |
Residue on Ignition | ≤0.1% | 0.00% |
Related Compounds | USP standard | Complies |
✔️ Heat-stable, light-stable in dry form
✔️ Slightly bitter taste
✔️ Compatible with dry blends, capsules, tablets
✔️ Reacts synergistically with other B vitamins
✅ Cellular Energy & Metabolism
Functions as a precursor for coenzymes NAD⁺ and NADP⁺, essential for energy production.
✅ Cholesterol & Lipid Management
Clinically shown to reduce LDL and triglycerides while boosting HDL levels.
✅ Nervous System & Cognitive Health
Supports brain function, neurotransmitter synthesis, and may help prevent age-related decline.
✅ Skin Health & Repair
Promotes healthy skin barrier and is used in treating pellagra (B3 deficiency).
✅ Vascular Support
Improves circulation and reduces oxidative stress in capillary walls.
✅ Detoxification & DNA Repair
Enhances phase I/II detox pathways and protects DNA from damage.
Use: Energy, lipid control, cognitive and skin support
Dosage: 100–1,000 mg/day for therapeutic uses
Form: Capsules, tablets, time-release formulations
Use: Functional drinks, energy foods, cereals
Dosage: 5–20 mg/serving
Form: Granular, premix or solution-phase systems
Use: Nutrient premix for metabolic regulation in livestock
Dosage: Species-specific formulations for poultry, cattle, aquaculture
Chemical Synthesis
→ Oxidation of 3-methylpyridine or 3-cyanopyridine to nicotinic acid
Crystallization & Purification
→ Filtration, recrystallization for USP/EP-grade material
Drying & Milling
→ Low-temperature dehydration and micronization
QC Testing
→ Assay (HPLC), melting point, drying loss, related compounds
Packaging
→ Light-blocking drums or bags under controlled conditions
Meets USP2022, EP10.0 – validated for food, pharma, and feed
Each batch independently tested and verified with COA
Vegan, non-GMO, gluten-free, and allergen-free
Bulk, private label, and formulation support available
Chibio’s Niacin provides businesses with a powerful, science-backed ingredient for:
Energy and endurance-focused nutrition
Cholesterol and vascular health formulas
Cognitive, skin, and cellular anti-aging products
Global-standard compliance for fortified food and pharma
✅ Whether you’re launching supplements, functional drinks, or wellness capsules, Chibio’s Vitamin B3 ensures efficacy, purity, and customer satisfaction.
Feature | Niacin (Nicotinic Acid) | Niacinamide (Nicotinamide) |
---|---|---|
Chemical Name | Nicotinic Acid | Nicotinamide |
CAS No. | 59-67-6 | 98-92-0 |
Molecular Formula | C₆H₅NO₂ | C₆H₆N₂O |
Solubility | Sparingly soluble in cold water, more in hot | Freely soluble in water & ethanol |
Taste & Stability | Slight bitterness; heat stable | Neutral taste; highly stable |
Metabolism Function | Precursor to NAD⁺/NADP⁺ | Also precursor to NAD⁺/NADP⁺ |
Flush Reaction | Yes – causes vasodilation and skin flushing | No flushing effect |
Cholesterol Impact | Reduces LDL & triglycerides; increases HDL | No significant lipid-modulating effect |
Skin Benefits | Less used in cosmetics | Excellent for brightening, anti-acne, and anti-aging |
Dosage – Supplements | 100–500 mg/day (max 2,000 mg in lipid control) | 100–500 mg/day standard; up to 1,000 mg/day for skin/cognition |
Topical Use | Rarely used | Widely used (2–10% in serums/creams) |
Applications | Cardiovascular supplements, detox, lipid support | Skin care, NAD+ boosters, wellness supplements |
Therapeutic Use | Hyperlipidemia, circulation, detox protocols | Acne, pigmentation, cognition, mental clarity |
Irritation Potential | Can cause flushing, tingling, itching | Generally well-tolerated |
Form Options | Powder, tablet, slow-release | Powder, capsule, cream, serum |
Choose Niacin (Nicotinic Acid) if your product is focused on:
Lipid modulation (cholesterol, triglycerides)
Detoxification and blood flow enhancement
Medical-grade cardiovascular formulations
Choose Niacinamide (Nicotinamide) if your product is designed for:
Skin brightening, acne control, or anti-aging formulas
NAD+ cellular energy boosting
Non-flushing vitamin B3 supplementation
Despite different metabolic paths and uses, both forms ultimately contribute to NAD⁺ and NADP⁺ formation, essential for energy metabolism, DNA repair, and anti-aging processes.
Looking for premium-grade Vitamin B3 (Niacin / Nicotinic Acid) for your nutritional or therapeutic product?
📧 Email: sales@chibiotech.com
📞 Phone: +86 (0)532 66983270
🌐 Website: www.chibiotech.com
✅ Chibio Biotech – Metabolic Wellness Starts with Precision Nutrition
Block B, Vanke Center, No.2 Heilongjiang South Road, Shibei District, Qingdao City, China 266033
+86 (0)532 66983270
+86 156 6577 2296
+86 133 8100 5417