Scleroglucan – High-Viscosity Biopolymer for Advanced Pharmaceutical, Cosmetic & Industrial Use

Natural Fermentation-Derived Exopolysaccharide for Functional Thickening, Stabilization & Film-Forming Applications

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Product Overview

Scleroglucan is a high-molecular-weight polysaccharide produced by the fermentation of Sclerotium rolfsii. It forms clear, stable, and high-viscosity solutions at low concentrations and exhibits excellent rheological properties in both aqueous and hydroalcoholic systems. It is widely used across pharmaceutical, personal care, and industrial formulations for its stability, skin compatibility, and unique functional behaviors.

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Basic Information

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Specification (Based on COA)​

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Physicochemical Properties

• Non-ionic, high-molecular-weight polysaccharide

• Excellent pseudoplastic (shear-thinning) behavior

• Stable over a wide pH range (3–11)

• Compatible with salts, alcohols, and surfactants

• Safe for skin contact and ingestion (GRAS in certain applications)

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Key Benefits

High viscosity at low concentrations
Non-toxic, biocompatible, and biodegradable
Stable in harsh conditions (pH, temperature, solvents)
Moisture-retention and skin-conditioning ability
Synergistic effects with other thickeners (e.g., xanthan, guar)

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Applications & Dosage Forms

Pharmaceutical Formulations

• Use: Bioadhesive gels, topical drug delivery, stabilizing emulsions

• Dosage: Typically 0.1%–1% in gels and creams

• Function: Enhances viscosity and skin feel while maintaining drug stability

Personal Care & Cosmetics

• Use: Facial gels, moisturizers, shampoos, sunscreens

• Dosage: 0.2%–1% for rheology control and texture enhancement

• Features: Leaves a soft film, enhances smoothness, compatible with ethanol-based formulas

Industrial Applications

• Use: Oilfield drilling fluids, paints & coatings, household care

• Dosage: Variable based on system (typically 0.5%–2%)

• Function: Stabilizer, suspending agent, thickener under extreme pH/salt conditions

Food & Nutraceutical (Where Permitted)

• Use: Functional dietary fiber, texture enhancer in processed foods

• Note: Regulatory status may vary by country

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Scleroglucan Production Flowchart

Fermentation
→ Sclerotium rolfsii cultivated under controlled bioreactor conditions

Biomass Harvesting
→ Mycelial exopolysaccharide (EPS) collected from fermentation broth

Purification
→ Filtration, precipitation with ethanol or isopropanol to isolate Scleroglucan

Drying
→ Vacuum or spray drying to obtain a fine, dry powder

Milling & Sieving
→ Particle size adjustment for end-use applications

Final QC & Packaging
→ Viscosity, microbiology, moisture control tests → Packaged in food/pharma-grade sealed bags

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Why Choose Chibio Biotech?

Expert in Fermentation Biopolymers

Backed by 8+ years in fungal chitosan & polysaccharide R&D and production

Quality Assured

ISO9001:2015 certified with rigorous testing for pharmaceutical and cosmetic grades

Versatile Supply Options

Custom grades, bulk availability, and global shipping

Sustainable & Clean Label

Natural fermentation origin, vegan, non-GMO, and biodegradable

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Request Free Sample or Quotation Now!

Looking for high-purity Scleroglucan for your cosmetic, pharmaceutical, or industrial formulation?

Email: sales@chibiotech.com
Phone: +86 (0)532 66983270
Website: www.chibiotech.com

Chibio Biotech – Powering Innovation with Natural Polysaccharides