Polyglutamic acid

Polyglutamic acid

Additional information

Product Name

Polyglutamic Acid (γ-PGA)

Source

Fermented soybeans or Bacillus subtilis

Appearance

White or almost white powder/granules

CAS Number

25513-46-6

Solubility

Water-soluble, Highly soluble (forms a clear, viscous solution)

Key Properties

Powerful moisturizing, anti-aging, and skin-repairing
✔ 5000x Water Retention Capacity – More effective than hyaluronic acid.
✔ Biodegradable & Non-Toxic – Safe for sensitive skin & eco-friendly formulations.
✔ pH Range: 5.0–7.5 – Ideal for cosmetic & dermatological applications​.

Main Applications

Cosmetics, Skincare, and Biomedical

Product Details

Polyglutamic Acid (γ-PGA) – The Ultimate Hydrating & Anti-Aging Ingredient

1. Introduction

Polyglutamic Acid (γ-PGA) is a biopolymer derived from fermented soybeans or Bacillus subtilis. It is widely known for its powerful moisturizing, anti-aging, and skin-repairing properties. Compared to hyaluronic acid (HA), γ-PGA offers superior hydration and enhanced water retention, making it a top ingredient in cosmetics, skincare, and biomedical applications​.

Chibio Biotech offers high-purity Cosmetic Grade γ-PGA to ensure optimal performance in skincare formulations.


2. Chemical Information of Polyglutamic Acid (γ-PGA)

  • CAS Number: 25513-46-6
  • Molecular Formula: (C5H7NO3)n
  • Molecular Weight: 100,000 – 2,000,000 Da (varies by grade)

Solubility

Water – Highly soluble (forms a clear, viscous solution)
Ethanol & Methanol – Slightly soluble
Oils & Non-Polar Solvents – Insoluble

📌 Key Properties:
5000x Water Retention CapacityMore effective than hyaluronic acid.
Biodegradable & Non-Toxic – Safe for sensitive skin & eco-friendly formulations.
pH Range: 5.0–7.5 – Ideal for cosmetic & dermatological applications​.


3. Technical Specification of Cosmetic Grade γ-PGA

Test Items Specification Results
Appearance White or almost white powder/granules Complies
Absorbance (4%, 400nm) ≤0.12 0.112
Transparency (0.5%, 400nm) ≥95.0% 97.4%
pH (1%) 5.0 – 7.5 5.7
Intrinsic Viscosity Actual value 0.84 dL/g
Loss on Drying ≤10.0% 8.5%
Heavy Metals (Pb) ≤10 ppm <10 ppm
Assay (Purity) ≥92.00% 95.2%
Total Bacterial Count ≤100 CFU/g <10 CFU/g
Molds & Yeasts ≤20 CFU/g <10 CFU/g
Staphylococcus Aureus Negative Negative
E. coli Negative Negative
Pseudomonas Aeruginosa Negative Negative

📌 Superior purity and safety standards for premium skincare formulations​.


4. Key Benefits of Polyglutamic Acid (γ-PGA)

💦 Ultra-Hydrating Power5000x water retention ability, significantly higher than Hyaluronic Acid (HA).
🛡 Strengthens Skin Barrier – Locks in moisture, improving elasticity and smoothness.
🔥 Anti-Aging & Wrinkle Reduction – Reduces fine lines and boosts collagen synthesis.
🌱 Brightens & Enhances Skin Tone – Promotes gentle exfoliation and cell renewal.
🧪 Increases Product Absorption – Enhances the effectiveness of active ingredients in skincare.


5. Applications of Polyglutamic Acid (γ-PGA)

Industry Recommended Use Application
Cosmetics & Skincare 0.1%-2% γ-PGA Moisturizers, serums, masks
Anti-Aging Products 1%-3% γ-PGA Wrinkle-reducing creams, lifting serums
Brightening & Hydration 1%-2% γ-PGA Toners, hydrating mists
Hair Care Products 0.5%-1.5% γ-PGA Conditioners, anti-frizz treatments
Biomedical & Wound Healing 2%-5% γ-PGA Skin repair creams, pharmaceutical applications

📌 Widely used in premium skincare formulations for deep hydration & anti-aging​.


6. Why Choose Chibio Biotech?

High-Purity Cosmetic Grade γ-PGA (≥95%) – Ensures maximum hydration & stability.
ISO Certified Production – Meeting global skincare & pharmaceutical standards.
Eco-Friendly & Biodegradable – Perfect for sustainable beauty formulations.
Non-GMO, Vegan & Cruelty-Free – Suitable for clean-label skincare brands.
Bulk Supply & Private Labeling – Available for custom formulations & packaging.


7. Why Should Your Business Use Polyglutamic Acid?

🚀 Increasing Market Demand for Advanced Hydration & Anti-Aging Ingredients – γ-PGA is a next-generation skincare ingredient.
💎 Clinically Proven for Moisturization, Wrinkle Reduction & Skin Elasticity – Trusted by leading beauty brands.
💰 High-Profit Cosmetic & Personal Care Ingredient – Ideal for luxury skincare, functional cosmetics & dermatological treatments.
🌍 Sustainable & Natural Alternative to Synthetic MoisturizersNon-toxic, biodegradable, and skin-friendly.


📩 Get in Touch for Premium Polyglutamic Acid (γ-PGA)!

Looking for high-quality γ-PGA (Polyglutamic Acid) for advanced skincare formulations? 🌿

📧 Email: sales@chibiotech.com
📞 Phone: +86 (0)532 66983270
🌍 Website: www.chibiotech.com
Hydrate, repair, and rejuvenate with Chibio Biotech’s premium Polyglutamic Acid! 🚀

Get in touch with us to boost your business

Headquarter

Block B, Vanke Center, No.2 Heilongjiang South Road, Shibei District, Qingdao City, China 266033

Phone

+86 (0)532 66983270

Cellphone / WhatsApp / WeChat

+86 156 6577 2296
+86 133 8100 5417

sales@chibiotech.com

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