💎 1. Product Introduction

Polydeoxyribonucleotide (PDRN) is a purified DNA-based bioactive ingredient extracted from natural sources and widely used in regenerative skincare. Known for stimulating tissue repair and anti-aging through cellular regeneration, PDRN is a next-generation cosmetic active that activates wound healing, promotes fibroblast growth, and enhances skin structure.

Chibio Biotech offers high-purity cosmetic grade PDRN (≥99%), ideal for premium serums, masks, and aesthetic applications.

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🧬 2. Source & CAS Number

• INCI Name: DNA Sodium

• Common Name: Polydeoxyribonucleotide (PDRN)

• CAS Number: 9007-49-2

• Molecular Weight: 60–100 kDa

• Origin: Natural DNA polymer (non-animal)

• Grade: Cosmetic Grade

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⚗️ 3. Chemical & Physical Properties

• Appearance: White to slightly yellowish powder or granules

• Assay (dry basis): ≥99.0%

• pH (1% solution): 6.0 – 8.0

• Molecular Weight: 60 – 100 KDa

• Solubility: Fully soluble in water

• Protein Content: ≤1.0%

• Moisture (Loss on Drying): ≤10.0%

• UV Ratio (A260/A280): 1.8 – 2.0

• Microbial Limits: Mold & yeast ≤ 100 cfu/g

• Shelf Life: 24 months under cool, dry storage

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💧 4. Solubility

• Water-soluble; forms clear solutions in aqueous cosmetic formulations

• Ideal for serums, gels, hydrogels, creams, and microneedle-compatible systems

• Compatible with hyaluronic acid, peptides, vitamins, and plant extracts

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✅ 5. Key Benefits

1. Accelerates Skin Repair – Stimulates fibroblast activity and extracellular matrix regeneration

2. Anti-Aging & Wrinkle Reduction – Enhances collagen synthesis and reduces fine lines

3. Brightens & Evens Skin Tone – Promotes cellular renewal and fades pigmentation

4. Improves Skin Elasticity – Increases dermal density and resilience

5. Anti-Inflammatory – Calms irritated, inflamed, or damaged skin

6. Hydration Support – Enhances moisture retention via improved cellular structure

7. Supports Aesthetic Recovery – Promotes rapid healing post-laser, microneedling, or mesotherapy

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🧬 6. Functions of PDRN

1. DNA Repair Activation

   PDRN supports the repair of damaged DNA structures in skin cells, enhancing cellular longevity and function.

2. Fibroblast Proliferation

   Directly stimulates fibroblast division, which increases production of collagen, elastin, and hyaluronic acid.

3. Tissue Regeneration

   Promotes angiogenesis and regeneration of extracellular matrix, especially after injury or inflammation.

4. Anti-Inflammatory Activity

   Modulates cytokine production and reduces oxidative stress in sensitive or aging skin.

5. Cell Signaling Enhancer

   Serves as a purinergic receptor activator, triggering skin regeneration cascades.

6. Wound Healing Promoter

   Accelerates epithelial regeneration, shortening recovery time in cosmetic and medical treatments.

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🧴 7. Applications

• Premium Skincare Serums

  – Skin repair concentrates, anti-aging ampoules, rejuvenating boosters

• Post-Treatment Recovery

  – After laser, microneedling, RF, or aesthetic procedures

• Hydrogels & Sheet Masks

  – High-efficacy face masks and hydration wraps

• Mesotherapy / Microneedle Cocktails

  – Formulated into injectable-free transdermal delivery systems

• Anti-Pigmentation & Tone Correctors

  – Combined with niacinamide or vitamin C to improve skin clarity

• Sensitive Skin Formulations

  – Used in redness-calming and barrier-repair solutions

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⚙️ 8. Production Process

DNA Material Selection & Extraction

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Hydrolysis to Optimal Molecular Weight (60–100 kDa)

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Purification & Protein Removal

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Drying & Granulation

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Final QC: HPLC, UV, Microbial Testing

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✅ Final Product: High-Purity Cosmetic Grade PDRN

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🏆 9. Why Choose Chibio Biotech?

• 🔬 DNA Actives Expertise – Advanced biopolymer purification and QC systems

• 💎 ≥99% Purity Guaranteed – HPLC-verified, batch-certified quality

• 🌿 Non-Animal, Non-GMO – Vegan-friendly, ethical sourcing

• 🧴 Wide Compatibility – Stable in most cosmetic and aesthetic formulations

• 🌍 Export-Ready – ISO, HALAL, KOSHER support for global markets

• 📦 Flexible MOQ & Packaging – Ideal for high-end brand launches

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💼 10. Why Your Brand Should Use PDRN

• Lead the market with DNA-based skincare innovation

• Provide rapid, visible skin recovery & regeneration in post-treatment formulas

• Boost customer trust with clinically recognized actives

• Offer non-invasive rejuvenation that rivals injectable therapies

• Tap into the luxury cosmetic trend for bio-intelligent actives

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📢 11. Summary 

Chibio’s Cosmetic Grade PDRN is the future of regenerative skincare — powered by DNA science, backed by purity, and ready to transform your cosmetic line. Join the global shift toward biotech beauty with the skin repair molecule trusted by professionals.

📩 Looking for a high-purity PDRN to enhance your skincare range?

Request specs, samples, or formulation support today!

📧 Email: sales@chibiotech.com

📞 Phone: +86 (0)532 66983270

🌍 Website: www.chibiotech.com

✅ Chibio Biotech – Where DNA meets dermocosmetics. 🧬💧