💎 1. Product Introduction

Nattokinase is a natural fibrinolytic enzyme extracted from Bacillus subtilis natto, the microorganism used to ferment traditional Japanese natto. This enzyme has gained significant global attention for its ability to support healthy blood circulation and cardiovascular function.

Nattokinase works by helping to break down fibrin, a protein involved in blood clot formation. Because of this mechanism, it is widely used in cardiovascular health supplements, functional foods, and nutraceutical formulations.

Chibio Biotech supplies high-purity Nattokinase with enzyme activity ≥20,000 FU/g, produced through controlled microbial fermentation and advanced purification processes to ensure consistent activity, safety, and stability.

---

🧬 2. Basic Information

Item	Details
Product Name	Nattokinase
Enzyme Source	Bacillus subtilis natto
Enzyme Activity	≥20,000 FU/g
Appearance	White or light yellow powder
Grade	Food Grade
Shelf Life	24 months

⚗️ 3. COA Specifications

Parameter	Specification	Result
Appearance	White or light yellow powder	Complies
Enzyme Activity	≥20,000 FU/g	21,000 FU/g
Moisture	≤8.0%	2.4%
Loss on Ignition	≤5.0%	2.1%
Lead (Pb)	≤5.0 mg/kg	<5.0 mg/kg
Arsenic (As)	≤3.0 mg/kg	<3.0 mg/kg
Total Plate Count	≤1000 CFU/g	300 CFU/g
Yeast & Mold	<100 CFU/g	<100 CFU/g
E. coli	Not detected in 10 g	Negative
Salmonella	Not detected in 10 g	Negative

💧 4. Solubility & Product Characteristics

• Easily soluble in water

• High enzymatic activity stability

• Sensitive to high temperature and extreme pH conditions

• Best stored in cool, dry conditions

Recommended storage:

• Temperature below 25°C

• Relative humidity below 60% 

---

🧬 5. Functional Benefits

1. Supports Healthy Blood Circulation

   Helps maintain normal blood flow by breaking down fibrin.

2. Cardiovascular Health Support

   Widely used in heart health supplements.

3. Natural Fibrinolytic Activity

   Helps regulate blood clotting balance.

4. Blood Pressure Support

   Research suggests potential benefits for maintaining healthy blood pressure.

5. Anti-thrombotic Activity

   Supports prevention of excessive clot formation.

6. Improved Vascular Health

   Helps maintain healthy blood vessel function.

---

🧴 6. Applications (Functions & Dosage Guidance)

💊 Cardiovascular Health Supplements

Function

• Supports healthy blood circulation

• Helps maintain cardiovascular wellness

• Provides natural fibrinolytic enzyme activity

Typical Dosage

• 100–200 mg per day (equivalent to 2000–4000 FU).

---

🧠 Healthy Aging Formulations

Function

• Supports vascular health in aging populations

• Helps maintain circulation and metabolic health

Typical Dosage

• 2000–4000 FU per day.

---

🧬 Functional Nutrition Products

Function

• Ingredient in heart health nutraceuticals

• Combined with ingredients such as CoQ10 or omega-3

Typical Inclusion

• Formulation dependent.

---

🥤 Functional Foods

Function

• Cardiovascular support ingredient in functional food products

Typical Inclusion

• Depends on regulatory limits and formulation.

---

⚙️ 7. Production Process Overview

Microbial Fermentation (Bacillus subtilis natto)

⬇

Enzyme Extraction

⬇

Purification

⬇

Concentration

⬇

Drying

⬇

Activity Testing

⬇

Packaging

---

🏆 8. Why Choose Chibio Biotech?

International Certifications

Chibio Biotech has obtained:

• ISO 22000 Certification

• HALAL Certification

• KOSHER Certification

• US FDA Food Facility Registration

Ensuring global regulatory compliance.

---

Strict Quality Control

• Enzyme activity verification

• Heavy metal monitoring

• Microbiological safety testing

• Batch COA traceability 

---

Stable Production Capacity

• Advanced microbial fermentation technology

• Consistent enzyme activity

• Reliable supply for global nutraceutical manufacturers.

---

Flexible Packaging

• Packaging available 20 kg or 50 kg drums 

• Custom packaging upon request.

---

11. Summary

Chibio’s Nattokinase (≥20,000 FU/g) is a high-activity fibrinolytic enzyme produced through controlled fermentation of Bacillus subtilis natto. With strong enzymatic activity, strict quality control, and international certification standards, it is an ideal ingredient for cardiovascular health supplements and advanced nutraceutical formulations.

📩 Looking for high-quality Nattokinase for your cardiovascular health products?

📧 Email: sales@chibiotech.com

📞 Phone: +86 (0)532 66983270

🌍 Website: www.chibiotech.com

✅ Chibio Biotech – Advanced Enzyme Ingredients for Cardiovascular Health & Nutritional Innovation. 🧬❤️✨

---