Melatonin – Natural Sleep Support & Circadian Rhythm Regulator

1. Introduction

Melatonin is a naturally occurring hormone secreted by the pineal gland in the brain, playing a crucial role in regulating the sleep-wake cycle (circadian rhythm). Widely used in nutraceuticals, pharmaceuticals, and functional health supplements, melatonin helps with insomnia, jet lag, sleep disorders, and stress management.

Chibio Biotech offers fermentation-derived high-purity melatonin (≥99.71%), suitable for global supplement and pharmaceutical applications​.

2. Chemical Information

• CAS Number: 73-31-4

• Chemical Name: N-Acetyl-5-methoxytryptamine

• Molecular Formula: C₁₃H₁₆N₂O₂

• Molecular Weight: 232.28 g/mol

Solubility

✔ Water – Slightly soluble
✔ Ethanol – Soluble
✔ DMSO – Soluble
✔ Oils – Insoluble

3. Technical Specifications ​

📌 Production Method: Fermentation
📌 Standards: Complies with USP43, EP10, BP

4. Key Benefits of Melatonin

🌙 Promotes Natural Sleep – Helps fall asleep faster and improve sleep quality
🕐 Regulates Circadian Rhythms – Ideal for shift workers and travelers
🌿 Reduces Jet Lag & Sleep Disorders – Balances internal sleep cycle
😌 Supports Mood & Anti-Stress – May alleviate anxiety and nighttime restlessness
🛡 Antioxidant & Immune Modulator – Helps reduce oxidative stress

5. Applications of Melatonin

6. Why Choose Chibio Biotech’s Melatonin?

✅ ≥99.7% High Purity – Fermentation Derived
✅ Non-GMO, Non-Irradiated, No Excipients
✅ USP, EP, BP Compliant for International Markets
✅ GMP Certified & ISO Standard Facility
✅ Low Impurity & Excellent Safety Profile

7. Why Should Your Business Use Melatonin?

🎯 Market Demand Is Exploding
Sleep-related products are one of the fastest-growing categories in global health and wellness. Consumers are actively seeking non-addictive, natural sleep solutions—and melatonin leads the category with a proven track record and widespread acceptance.

💡 Backed by Science & Global Regulations
Melatonin is clinically validated and recognized by major pharmacopoeias (USP, EP, BP). It’s safe, effective, and supported by real-world use in 100+ countries, making it a reliable and low-risk ingredient for product development.

🌿 Natural, Fermentation-Derived & Clean Label
Chibio Biotech’s melatonin is fermented, non-synthetic, and non-GMO. Perfect for brands focused on clean-label formulations, vegan claims, and consumer trust.

🔬 Ultra-Pure & Consistent Quality (≥99.7%)
Whether you’re formulating capsules, tablets, sprays, or beverages, purity matters. Our USP/EP/BP-compliant melatonin ensures predictable results, safety, and global regulatory acceptance, reducing development risk.

💰 Cost-Effective & Versatile Across Product Categories
Use melatonin in:

• Sleep support capsules & gummies

• Nighttime functional beverages

• Jet lag and travel-focused formulations

• Anti-stress, calm, and mood support lines

This versatility offers multiple revenue streams across wellness, pharmaceutical, and functional food sectors.

📦 Available in Flexible MOQ & Ready Samples
We understand the importance of trial, testing, and speed-to-market. That’s why we offer:

• Free or low-cost samples for R&D

• Small MOQ to help your project start lean

• Full technical support & COA documentation

📩 Contact Us for Premium Melatonin Supply!

Looking for high purity melatonin for your brand or formulation?

📧 Email: sales@chibiotech.com
📞 Phone: +86 532 66983270
🌍 Website: www.chibiotech.com
✅ Support restful sleep and wellness with Chibio Biotech’s premium melatonin!