L-Se-Methylselenocysteine (L-SeMC)

L-Se-Methylselenocysteine (L-SeMC)

Additional information

Product Name

L-Se-Methylselenocysteine

CAS Number

1464-43-5

Appearance

White powder or granule, garlic-like odor

Key Properties

High bioavailability, low toxicity, and potent antioxidative and anti-inflammatory properties

Main Benefits

✅ Superior Selenium Bioavailability
🛡 Antioxidant & Detoxification
🧬 DNA Repair & Anti-cancer Support
💊 Thyroid Function & Hormonal Balance
🧠 Neuroprotection & Cognitive Support
❤️ Cardiovascular Protection

Main Applications

1. Nutraceuticals & Dietary Supplements
2. Functional Foods & Beverages
3. Cosmeceuticals & Skin Health
4. Veterinary & Animal Nutrition
5. Medical Nutrition & Oncology Research

Product Details

L-Se-Methylselenocysteine (L-SeMC) – High-Bioavailability Organic Selenium Source

Chinese Name: L-硒-甲基硒代半胱氨酸
Grade: Food Grade
CAS Number: 1464-43-5
Chemical Formula: C4H9NO2Se | Molecular Weight: 184.08 g/mol
Form: White powder or granules with garlic-like odor


🧪 1. Product Overview

L-Se-Methylselenocysteine (L-SeMC) is a naturally occurring organic selenium compound found in Allium (garlic, onion) and Brassica (broccoli, cabbage) vegetables. It is widely recognized as the most effective and safest form of selenium supplementation, offering high bioavailability, low toxicity, and potent antioxidative and anti-inflammatory properties.

L-Se-Methylselenocysteine is a natural selenium compound found in plants like garlic and broccoli. Unlike other forms (e.g., selenite, selenomethionine), L-SeMC provides directly usable selenium for cellular defense, with high bioavailability, antioxidant synergy, and excellent safety.


📊 2. Technical Specifications 

Item Specification Result
Appearance White powder or granule, garlic-like odor Complies
L-SeMC Content ≥96% 99.3%
Specific Rotation (aqueous) -13
Loss on Drying ≤1.0% 0.6%
pH (1% solution) 4.5 – 6.5 5.5
Total Arsenic (As) ≤2.0 mg/kg Not detected
Lead (Pb) ≤2.0 mg/kg Not detected
Microbial Limit Meets GB1903.12 food safety standard Passed

Complies with GB1903.12 national food safety standards


💧 3. Solubility

  • Water: Freely soluble

  • Ethanol: Slightly soluble

  • Oil: Insoluble


🌱 4. Core Benefits & Functional Properties

  • Superior Selenium Bioavailability – >90% absorption vs. inorganic selenium

  • 🛡 Antioxidant & Detoxification – Neutralizes free radicals and supports glutathione activity

  • 🧬 DNA Repair & Anti-cancer Support – Promotes apoptosis in abnormal cells

  • 💊 Thyroid Function & Hormonal Balance – Selenium is essential for T3–T4 conversion

  • 🧠 Neuroprotection & Cognitive Support – Linked to reduced risk of neurodegenerative decline

  • ❤️ Cardiovascular Protection – Reduces inflammatory markers and oxidative stress


📈 5. Application Areas & Recommended Dosage

1. Nutraceuticals & Dietary Supplements

  • 💊 Capsules & tablets for:

    • Immune health

    • Thyroid support

    • Detoxification formulas

  • Suggested dosage: 50–200 µg selenium/day

  • L-SeMC yields approx. 400–500 µg selenium per mg.


2. Functional Foods & Beverages

  • 🥤 Added to:

    • Fortified juices or water-soluble sachets

    • Daily wellness blends (with zinc, vitamins C & E)

  • Dosage: 50–100 µg selenium/serving

  • Water-soluble, neutral taste in small amounts


3. Cosmeceuticals & Skin Health

  • 🌿 Topical or oral use for:

    • Antioxidant skin care (with glutathione, CoQ10)

    • Scalp/hair vitality products

  • Typical usage: 0.01–0.1% in creams or lotions


4. Veterinary & Animal Nutrition

  • 🐕🐓🐄 Used in:

    • Poultry & swine feed premixes

    • Pet supplements for antioxidant & immune protection

  • ✅ Dosage: 0.2–0.5 mg selenium/kg feed (adjust based on selenium yield)


5. Medical Nutrition & Oncology Research

  • 📚 In clinical study pipelines for:

    • Anti-tumor adjuvant therapy (chemoprevention)

    • Neuroprotective dietary support

  • ✅ Delivered in clinical formulas (under research)

Application Purpose Suggested Dosage
Nutraceuticals Capsules, tablets for antioxidant and detox formulas 50–200 µg/day selenium equivalent
Functional Foods Fortified foods, beverages 20–100 µg/serving
Cosmetics (Emerging) Anti-aging skin care, scalp health 0.01–0.1% (water-soluble formats)
Animal Nutrition Organic selenium for livestock, poultry 0.2–0.5 mg/kg of feed

📌 1 mg L-SeMC contains approx. 400–500 µg selenium, adjust dosing carefully.


📊 6. Advantages Over Other Selenium Sources

Selenium Type Absorption Toxicity Stability Formulation Flexibility
L-SeMC ★★★★★ Low Stable in powder form Excellent (capsules, foods)
Sodium Selenite ★★ High Less stable Limited use
Selenomethionine ★★★★ Moderate Moderate Common in supplements
Yeast Selenium ★★★ Moderate Variable Needs organic Se validation

🧠 L-SeMC is regarded as the most stable and bioavailable selenium form for functional food and nutraceutical applications.


📦7.  Packaging & Shelf Life

  • Packing: 100galuminum foil bags; 25kg/drum

  • Shelf Life: 24 months in sealed container under cool, dry, dark conditions


⚙️ 8. Production Flowchart (Simplified)

  1. Raw Material Selection
    → High-purity precursors with selenium enrichment

  2. Synthesis Reaction
    → Controlled reaction to form L-Se-methylselenocysteine

  3. Purification & Crystallization
    → Remove by-products, achieve ≥99% purity

  4. Drying & Granulation
    → Spray or vacuum drying to produce stable powder

  5. Screening & QC Testing
    → Mesh sizing, HPLC assay, microbial & heavy metal testing

  6. Packaging
    → Aluminum foil or drum; nitrogen protection optional


🔍 8. Why Use L-Se-Methylselenocysteine in Your Business?

  • 🔬 Scientifically Superior Organic Selenium – High purity (99.3%), low heavy metals, safe and effective

  • 📈 Market Demand for Antioxidant and Immunity Solutions – Especially in post-pandemic immune health, detox, and anti-aging sectors

  • 🧪 Multi-Industry Use – Ideal for dietary supplements, functional foods, beauty-from-within, and even pet nutrition

  • 🌍 Clean Label Ready – Vegan, non-GMO, allergen-free, and water-soluble

  • 💼 Premium Positioning – Allows higher pricing, better claims, and stronger scientific backing than basic selenium forms

Feature Value
High absorption rate Over 90% selenium bioavailability
Safety Low toxicity, even at higher concentrations
Efficacy Directly incorporated into antioxidant systems (e.g., GPx enzymes)
Stability Excellent shelf stability, no need for refrigeration
Label-Friendly Clean label, organic selenium, vegan, gluten-free
Differentiation Premium position compared to selenomethionine or selenite

💼9.  Why Choose Chibio Biotech?

1. Precision in Quality & Purity

  • ≥99.3% Purity L-SeMC based on validated HPLC methods

  • Strict compliance with GB1903.12, USP, and food-grade safety standards

  • Tested for heavy metals, microbial load, and stability — every batch with COA, MSDS, and TDS


🔬 2. Scientific Ingredient Expertise

  • Specialized in high-activity, bioavailable ingredients such as L-SeMC, NMN, Beta Glucan, etc.

  • Ability to explain and support health claims through scientific data

  • Custom formulation support: blends with vitamin E, glutathione, or selenium yeast if needed


🌱 3. Clean, Traceable & Safe

  • Food-grade, vegan, non-GMO, and non-toxic formulations

  • Transparent sourcing and processing – free from unwanted additives, preservatives, or artificial carriers

  • Meets international regulations (EU, USA, APAC) for nutritional and functional foods


🏭 4. Advanced Production Facilities

  • GMP-certified production lines

  • Clean-room environments, proprietary drying and crystallization processes

  • Custom packaging available (1g–25kg), nitrogen-sealed upon request


📈 5. Supply Chain Strength & Service Excellence

  • Consistent inventory and reliable bulk supply capacity

  • Professional logistics handling for sensitive bioactive compounds

  • Fast response for sampling, documentation, and formulation consultation


💡 6. Innovation-Driven Product Portfolio

  • Over 200+ specialty ingredients across:

    • Immunity & detox

    • Brain & longevity

    • Functional beauty & active aging

  • Always updated with the latest science and market trends


📩 Interested in premium selenium innovation for your product lines?
📧 Email: sales@chibiotech.com | 🌐 www.chibiotech.com | 📞 +86 532 66983270
Chibio Biotech – Precision Ingredients for Functional Health Solutions

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Phone

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