HMB

HMB

Additional information

Product Name

HMB (β-Hydroxy β-Methyl-Butyric)

Specification

HMB Free Acid (FA) in Liquid Form
HMB Calcium (Ca-HMB) in Powder Form

Cas Number

625-08-1 (HMB Free Acid)
135236-72-5 (HMB Calcium)

Main Benefits

💪 Muscle Growth & Strength
⚡ Faster Recovery
🔥 Fat Loss & Lean Muscle Retention
🏃 Improves Endurance & Performance
🛡️ Anti-Catabolic Properties
🦴 Supports Bone Health

Main Applications

🏋️ Sports Nutrition
🥤 Functional Beverages
💊 Dietary Supplements
🦴 Bone Health Supplements
⚕ Medical Nutrition

Product Details

HMB (β-Hydroxy β-Methyl-Butyric) – The Ultimate Muscle & Performance Enhancer!

1. Introduction

HMB (β-Hydroxy β-Methyl-Butyric) is a naturally occurring metabolite of the essential amino acid Leucine. It plays a vital role in muscle growth, recovery, and reducing muscle breakdown, making it a popular ingredient in sports nutrition and dietary supplements.


2. Source & CAS Number

  • Source: Derived from Leucine metabolism
  • CAS Number: 625-08-1 (HMB Free Acid) / 135236-72-5 (HMB Calcium)

3. Chemical Structure

HMB Free Acid (FA)

Molecular Formula: C5H10O3
Structure:
🧪 More bioavailable, faster absorption

HMB Calcium (Ca-HMB)

Molecular Formula: C10H18CaO6
Structure:
🦴 More stable, extended release

📌 Both forms support muscle retention, strength, and endurance.


4. Specifications & Comparison (HMB Ca Powder vs. HMB Liquid)

Item HMB Ca Powder HMB Liquid (HMB Free Acid) Key Differences
Appearance White crystalline powder Colorless to yellow liquid Powder is more stable; liquid absorbs faster
HMB Assay ≥84.0% ≥95.0% Free acid has higher purity
pH Neutral 1.0 – 4.0 Liquid is acidic, better for absorption
Calcium Content 13.6-14.8% None HMB Ca provides calcium benefits
Solubility Slightly soluble in water Highly soluble in water Liquid dissolves instantly
Heavy Metals ≤10 ppm ≤10 ppm Both meet strict safety standards
Shelf Life 2 years 2 years Both have long-term stability
Storage Dry, cool place Sealed, away from moisture Proper storage ensures effectiveness

📌 HMB Ca Powder: Best for stable formulations like capsules & powders.
📌 HMB Liquid (FA): Best for fast-acting liquid supplements & beverages.


5. Solubility & Stability

  • HMB Ca Powder: Slightly soluble in water, better mixed in solid formulations.
  • HMB Liquid (FA): Completely water-soluble, allowing for fast absorption.
  • Storage: Keep both in dry, sealed containers, away from direct light & heat.

6. Benefits of HMB

💪 Muscle Growth & Strength – Stimulates protein synthesis and reduces muscle breakdown.
Faster Recovery – Helps muscles recover quickly after intense workouts.
🔥 Fat Loss & Lean Muscle Retention – Preserves muscle while reducing fat.
🏃 Improves Endurance & Performance – Enhances stamina and exercise capacity.
🛡️ Anti-Catabolic Properties – Protects muscles from stress and overtraining damage.
🦴 Supports Bone Health – HMB Ca provides additional calcium for stronger bones.


7. Applications of HMB

🏋️ Sports Nutrition – Muscle-building powders, pre/post-workout supplements.
🥤 Functional Beverages – Energy drinks, protein shakes.
💊 Dietary Supplements – Tablets, capsules, effervescent formulations.
🦴 Bone Health Supplements – HMB Ca for osteoporosis prevention.
Medical Nutrition – Supports muscle maintenance in aging populations.


8. Flowchart of HMB Ca Powder (β-Hydroxy β-Methyl-Butyric Calcium)

The production process of HMB-Ca (Calcium β-Hydroxy β-Methyl-Butyrate) involves multiple purification and reaction steps to ensure high purity and bioavailability.

📌 Step-by-Step Production Process

1️⃣ Raw Material Oxidation

  • Diacetone Alcohol is oxidized using sodium hypochlorite (NaClO).
  • This step produces an intermediate that undergoes further reactions.

2️⃣ Neutralization & Concentration

  • The reaction product is neutralized with HCl (hydrochloric acid).
  • The mixture is concentrated under vacuum to remove excess solvents and by-products.

3️⃣ Extraction & Purification

  • The concentrated solution is extracted using ethyl acetate to isolate the desired compound.
  • Unwanted impurities are removed in this process.

4️⃣ Filtration & Refinement

  • The solution is filtered to remove sodium chloride (NaCl), a by-product.
  • The crude HMB is further refined and purified.

5️⃣ Rectification & Isolation of HMB

  • The refined HMB undergoes rectification, a purification process to enhance purity.
  • The isolated HMB is ready for calcium salt conversion.

6️⃣ Reaction with Calcium Salt

  • HMB reacts with calcium hydroxide (Ca(OH)₂) in the presence of ethyl alcohol.
  • This forms HMB-Ca (Calcium β-Hydroxy β-Methyl-Butyrate) in a stable crystalline form.

7️⃣ Crystallization & Drying

  • The HMB-Ca crystallizes and is dried under vacuum to remove residual solvents and moisture.

8️⃣ Final Processing & Packaging

  • The dried crystals undergo crushing and screening to ensure uniform particle size.
  • The final HMB-Ca powder is packed in sealed containers, ready for distribution.

📌 Key Features of the HMB-Ca Production Process

High Purity (≥99.0%) – Advanced rectification and filtration ensure minimal impurities.
Stable & Bioavailable – The calcium salt form enhances solubility and stability.
Strict Quality Control – Heavy metal limits and microbial safety checks ensure safe consumption.
Versatile Form – Suitable for capsules, tablets, and powder blends in sports and medical nutrition.


9. Why Choose Chibio Biotech?

High Purity & Bioavailability – 99% pure HMB for maximum effectiveness.
Multiple Forms AvailableHMB Ca Powder & HMB Liquid to suit different formulations.
Certified & SafeGMO-Free, Non-Irradiated, meets global safety standards.
Customizable Supply – Bulk orders, private labeling, and OEM solutions.
Proven Efficacy – Used by athletes, fitness enthusiasts, and medical professionals worldwide.


10. Why Should Your Business Consider HMB?

📈 Expanding Sports Nutrition Market – Growing demand for muscle-enhancing supplements.
🌍 Scientific Validation – Extensive research backing HMB’s role in muscle health.
🏆 Versatile Applications – Ideal for powders, drinks, capsules, and medical nutrition.
🛒 Higher Consumer Demand – Athletes & aging individuals seek muscle-preserving solutions.

💡 Ready to upgrade your sports & health formulations? Let’s work together!


📩 Get in Touch for Premium HMB!

Looking for high-quality HMB Calcium or HMB Free Acid for your supplements, beverages, or medical applications? 🌿

📧 Email: sales@chibiotech.com
📞 Phone: +86 (0)532 66983270
🌍 Website: www.chibiotech.com
Maximize muscle growth, strength, and recovery with Chibio Biotech’s HMB – The Ultimate Performance Booster! 🚀

Get in touch with us to boost your business

Headquarter

Block B, Vanke Center, No.2 Heilongjiang South Road, Shibei District, Qingdao City, China 266033

Phone

+86 (0)532 66983270

Cellphone / WhatsApp / WeChat

+86 156 6577 2296
+86 133 8100 5417

sales@chibiotech.com

Let's get in touch to start 100% natural plant-based life NOW!