Hydroxymethylbutyrate (HMB) is a chemical that is produced when the body breaks down leucine. Leucine is an amino acid, one of the building blocks of protein. People use HMB to make medicine.
HMB, or beta-hydroxy beta-methylbutyric acid, is an active metabolite of the amino acid leucine, meaning a portion of leucine is metabolized into HMB once in the body. Leucine is the branched chain amino acid most responsible for protein synthesis, or muscle growth. HMB, in its supplemental from, is commonly used by bodybuilders or athletes who are interested in increasing the benefits of strength training.
According to a Vanderbilt University health psychology report, researchers concur that, although the mechanism by which HMB effects muscle function is still unknown, HMB may inhibit protein degradation during periods of resistance training. According to a study published in the European Journal of Applied Physiology, HMB, though not as effective as leucine in building muscle, is significantly more effective in preventing muscle breakdown. Therefore, it is marketed by most supplement manufacturers as an anti-catabolic agent as opposed to simply a muscle building supplement.
Specification of HMB
|Characters/appearance||Yellow Liquid/White Powder||Complies|
|Residue on Ignition||≤1%||0.8%|
Benefits & Applications of HMB
HMB is derived from the essential amino acid leucine. A substantial body of evidence suggests that leucine when combined with proper training increases strength, decreases body fat, decreases muscle breakdown, stimulates protein synthesis, and decreases soreness. Similarly, research implies that HMB supplementation exhibits both pro-growth and anti-breakdown properties like its parent compound leucine. Moreover, some investigation even suggets that HMB may be more effective at reducing muscle breakdown when compared to leucine.