💎 1. Product Introduction

Creatine Monohydrate is one of the most researched and widely used performance-enhancing ingredients in sports nutrition. It supports rapid ATP regeneration in muscle cells, improving strength, power output, and muscle endurance.

Chibio Biotech supplies USP-grade Creatine Monohydrate (200 mesh) with high purity (99.5–102%), extremely low impurity levels, and strict microbiological control  . The fine particle size ensures excellent dispersibility and formulation flexibility.

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🧬 2. Basic Information

• Product Name: Creatine Monohydrate

• Formula: C₄H₉N₃O₂·H₂O 

• Standard: USP 

• Appearance: White powder 

• Particle Size: 200 mesh (≥70% through 200 mesh) 

• Shelf Life: 24 months 

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⚗️ 3. Technical Specifications

According to the COA  :

Assay & Purity

• Content (Dry Basis): 99.5–102.0%

• Total Impurities: ≤2.0%

• Creatinine: ≤100 ppm

• Dicyandiamide: ≤50 ppm

• Dihydrotriazine: ≤0.0005%

• Any Unspecified Impurity: ≤0.1%

Physical & Chemical

• Loss on Drying: 10.5–12.0%

• Residue on Ignition: ≤0.1%

• Bulk Density: ≥400 g/L

• Tapped Density: ≥550 g/L

Heavy Metals

• Total Heavy Metals: ≤10 ppm

• Lead: ≤0.1 ppm

• Mercury: ≤0.01 ppm

• Arsenic: ≤1 ppm

• Cadmium: ≤1 ppm

Microbiological Safety

• Total Bacterial Count: ≤100 cfu/g

• Yeast & Mold: ≤100 cfu/g

• E. coli, Salmonella, Staphylococcus Aureus: Not detected

These results confirm pharmaceutical-grade purity and safety.

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💧 4. Solubility & Stability

• Moderately soluble in water

• Stable under dry conditions

• Slightly hygroscopic

• Compatible with powder blends, capsules, tablets, and RTD beverages

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✅ 5. Key Benefits

1. Clinically Proven Performance Ingredient

2. High Purity (USP Grade)

3. Extremely Low Impurity Levels

4. Fine 200 Mesh Particle Size for Easy Mixing

5. Excellent Safety Profile

6. Supports Muscle Strength & Recovery

7. Suitable for Global Export Markets

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🧬 6. Functions of Creatine Monohydrate

1. ATP Regeneration Support

   Enhances phosphocreatine stores in muscle cells.

2. Strength & Power Enhancement

   Increases maximal strength and explosive performance.

3. Muscle Mass Support

   Promotes muscle volumization and protein synthesis.

4. Exercise Recovery Improvement

   Reduces muscle fatigue and improves training capacity.

5. Cognitive Support (Emerging Research)

   Supports brain energy metabolism.

6. Lean Body Composition Enhancement

   Helps improve muscle-to-fat ratio when combined with training.

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🧴 7. Applications (Detailed Functional Description & Dosage Recommendations)

🏋️ Sports Nutrition Supplements

Function:

• Enhances muscle phosphocreatine levels

• Increases short-term high-intensity performance

• Improves strength gains in resistance training

• Supports faster recovery between sets

Recommended Dosage:

• Loading Phase (Optional): 15–20 g/day divided into 3–4 doses for 5–7 days

• Maintenance Phase: 3–5 g/day

• Can be taken pre- or post-workout

• Best combined with carbohydrates for enhanced uptake

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💪 Muscle Building & Weight Gain Formulas

Function:

• Supports lean muscle mass development

• Enhances nitrogen retention

• Improves training adaptation

Recommended Dosage:

• 3–5 g per serving

• Typically included in mass gainer formulas at 2–5 g per serving

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🧠 Cognitive & Energy Support Formulations

Function:

• Supports brain ATP metabolism

• May enhance mental performance under fatigue

Recommended Dosage:

• 2–5 g/day

• Often combined with B vitamins or nootropics

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🥤 Functional Beverages & Ready-to-Drink (RTD)

Function:

• Provides performance positioning

• Enhances workout-focused beverages

Recommended Inclusion:

• 2–3 g per bottle

• Ensure proper solubilization and pH control

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💊 Capsules & Tablets

Function:

• Convenient dosage form

• Controlled daily intake

Typical Capsule Dosage:

• 750 mg – 1000 mg per capsule

• 3–5 capsules daily depending on target dose

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⚠ Note: Dosage may vary depending on regulatory guidelines, body weight, and athletic goals. Always comply with local dietary supplement regulations.

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⚙️ 8. Production Process Overview

Raw Material Synthesis

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Crystallization

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Drying

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Milling (200 Mesh Control)

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USP Testing (HPLC, Impurities, Heavy Metals)

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Microbiological Testing

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Final Packaging

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🏆 9. Why Choose Chibio Biotech?

Certified & Compliant Manufacturing

• USP standard compliance 

• Strict heavy metal control

• Batch-based COA documentation

High Purity & Low Impurity Profile

• Creatinine ≤100 ppm

• Dicyandiamide ≤50 ppm

• Total impurities extremely low

Stable Supply Capacity

• 1000 kg batch production 

• Export-ready quality documentation

Professional Technical Support

• Formulation assistance

• Stability and solubility guidance

• Custom packaging options

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11. Summary

Chibio’s Creatine Monohydrate (USP Grade, 200 Mesh) delivers high purity, low impurity levels, and proven performance benefits for sports nutrition, muscle building, and functional formulations. With strict quality control and excellent microbiological safety, it supports reliable, high-performance supplement development.

📩 Looking for pharmaceutical-grade Creatine Monohydrate for your sports nutrition brand?

📧 Email: sales@chibiotech.com

📞 Phone: +86 (0)532 66983270

🌍 Website: www.chibiotech.com

✅ Chibio Biotech – Advanced Performance Ingredients for Modern Nutrition. 💪✨