High-Purity Coenzyme Q10 (98% Oil-Soluble & 10%/20% Water-Soluble) for Dietary Supplements, Cosmetics, and Pharmaceuticals

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1. Introduction to Coenzyme Q10

Coenzyme Q10 (CoQ10), also known as ubiquinone, is a fat-soluble antioxidant that plays a critical role in cellular energy production and cardiovascular health. It is widely used in nutritional supplements, skincare, and pharmaceutical formulations.

At Chibio Biotech, we offer:

• Coenzyme Q10 98% (Oil-Soluble) – Ideal for softgel capsules, functional foods, and cosmetics.
• Coenzyme Q10 10% & 20% (Water-Soluble) – Perfect for beverages, liquid formulations, and instant powders.

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2. Source & Basic Information

Source of Coenzyme Q10

Coenzyme Q10 (CoQ10, Ubiquinone) is a naturally occurring antioxidant found in human cells, animals, and some plants. However, the commercial production of CoQ10 is primarily achieved through fermentation or chemical synthesis to ensure high purity, stability, and cost-effectiveness.

Natural Sources of Coenzyme Q10 (in small amounts):

🥩 Animal-Based Sources:

• Organ meats (heart, liver, kidney) – Highest natural concentration
• Fatty fish (sardines, mackerel, salmon, tuna)
• Egg yolks and dairy products

🥬 Plant-Based Sources (Lower content than animal sources):

• Spinach, broccoli, cauliflower
• Legumes (soybeans, peanuts, lentils)
• Nuts & seeds (pistachios, sesame seeds, walnuts)

💊 Commercial Production Sources:
1️⃣ Microbial Fermentation (Preferred Method) –

• Uses yeast (Candida, Rhodobacter) or bacteria to naturally ferment and produce CoQ10.
• Results in high-purity, bioidentical CoQ10 (same structure as human-produced CoQ10).
• Most widely used for supplements, functional foods, and pharmaceuticals.

2️⃣ Chemical Synthesis (Less Common) –

• Uses chemical precursors to synthesize CoQ10.
• More cost-effective but lower bioavailability than fermented CoQ10.

📌 Which Source is Better?
✔ Microbial fermentation-derived CoQ10 is higher quality, more natural, and bioidentical to the body’s CoQ10.
✔ Synthetic CoQ10 is cheaper but less effective in absorption and bioavailability.

🔬 Chibio Biotech’s Coenzyme Q10 is produced through advanced microbial fermentation, ensuring:
✅ High purity (≥98%)
✅ Better bioavailability
✅ Suitable for dietary supplements, cosmetics, and functional foods

Conclusion:
While CoQ10 is naturally present in animal and plant sources, commercially available CoQ10 is typically derived from fermentation to ensure purity, effectiveness, and large-scale production. 🚀✨

• Product Name: Coenzyme Q10 (Ubidecarenone)
• CAS Number: 303-98-0
• Molecular Formula: C₅₉H₉₀O₄
• Molecular Weight: 863.34 g/mol
• Appearance: Yellow to orange crystalline powder
• Odor & Taste: Odorless, neutral taste

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3. Product Specifications & Types

Component	Coenzyme Q10 98% (Oil-Soluble)	Coenzyme Q10 10% (Water-Soluble)	Coenzyme Q10 20% (Water-Soluble)
Solubility	Insoluble in water, soluble in oils, fats, and organic solvents	Easily dispersible in cold water (15°C) to form a uniform emulsion	Easily dispersible in cold water (15°C) to form a uniform emulsion
Assay (HPLC)	≥98.0%	≥10.0%	≥20.0%
Melting Point	48ºC-52ºC	N/A	N/A
Water Content	≤0.2%	≤5.0%	≤5.0%
Particle Size	100% pass 80 mesh	100% pass 40 mesh	90% pass 60 mesh
Heavy Metals (Pb, As, Hg, Cd)	Complies	Complies	Complies
Microbial Quality	TPC ≤1000 cfu/g, Yeast & Mold ≤50 cfu/g, Pathogens – Negative	TPC ≤1000 cfu/g, Yeast & Mold ≤100 cfu/g, Pathogens – Negative	TPC ≤1000 cfu/g, Yeast & Mold ≤100 cfu/g, Pathogens – Negative
Shelf Life	24 months	24 months	24 months
Storage	Store in a cool, dry place, away from direct sunlight	Store in a cool, dry place, away from direct sunlight	Store in a cool, dry place, away from direct sunlight

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4. Functional Properties & Solubility

• Coenzyme Q10 98% (Oil-Soluble): Best for oil-based applications, including softgel capsules, creams, and functional foods.
• Coenzyme Q10 10% & 20% (Water-Soluble): Designed for water-based applications, including beverages, instant drinks, and liquid supplements.

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5. Key Advantages & Benefits

✅ Enhances Energy Production – Supports mitochondrial function and ATP synthesis.
✅ Powerful Antioxidant & Anti-Aging – Neutralizes free radicals and reduces oxidative stress.
✅ Promotes Heart Health – Improves cardiovascular function and circulation.
✅ Boosts Brain & Cognitive Function – May help protect against neurodegenerative diseases.
✅ Supports Skin Health – Reduces wrinkles, improves elasticity, and protects against UV damage.
✅ Highly Bioavailable Options – Oil-soluble for lipid-based formulations, water-soluble for beverages & fast absorption.

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6. Applications of Coenzyme Q10

A. Dietary Supplements & Nutraceuticals

🔹 Softgel Capsules & Tablets – Common in anti-aging, heart health, and energy-boosting formulations.
🔹 Liquid & Powdered Supplements – Used in fast-acting water-dispersible formulations.
🔹 Sports Nutrition – Enhances energy metabolism and muscle recovery.

B. Functional Foods & Beverages

🔹 Energy Drinks & Wellness Beverages – Water-soluble Q10 used in functional drinks.
🔹 Fortified Dairy & Protein Products – Enhances nutrient content in yogurts and protein shakes.
🔹 Bakery & Confectionery – Used in fortified chocolates and gummies.

C. Skincare & Cosmetics

🔹 Anti-Aging Creams & Serums – Reduces fine lines and oxidative skin damage.
🔹 Sunscreen & UV Protection – Protects against photoaging and skin damage.
🔹 Hair Care & Scalp Treatments – Improves hair growth and scalp health.

D. Pharmaceutical & Medical Applications

🔹 Cardiovascular Health – Used in prescription formulations for heart conditions.
🔹 Neuroprotection & Cognitive Health – Investigated for Parkinson’s, Alzheimer’s, and neurodegenerative diseases.

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7. Choosing the Right Type of Coenzyme Q10

Application	Best Type of Coenzyme Q10
Softgel Capsules & Oil-Based Supplements	Coenzyme Q10 98% (Oil-Soluble)
Liquid Beverages & Instant Powders	Coenzyme Q10 10% or 20% (Water-Soluble)
Anti-Aging Skincare & Creams	Coenzyme Q10 98% (Oil-Soluble)
Energy & Sports Drinks	Coenzyme Q10 20% (Water-Soluble)
Tablets & Dry Powder Supplements	Coenzyme Q10 10% or 20% (Water-Soluble)
Medical Formulations (Cardiovascular, Neuroprotection, etc.)	Coenzyme Q10 98% (Oil-Soluble)

🔹 For maximum bioavailability in oil-based formulations → Choose CoQ10 98% (Oil-Soluble).
🔹 For quick dispersion in water-based drinks & liquid supplements → Choose CoQ10 10% or 20% (Water-Soluble).

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8. Production Flowchart of Coenzyme Q10

Brief Description of the Coenzyme Q10 Production Process

1️⃣ Fermentation – The process starts with Rhodobacter sphaeroides, a specialized bacterial strain used to naturally produce Coenzyme Q10 through microbial fermentation.

2️⃣ Bacterial Inactivation – The bacterial activity is stopped to prevent further metabolic reactions.

3️⃣ Plate Filtration – The fermentation broth is filtered to remove impurities and bacterial residues, leaving behind a CoQ10-rich solution.

4️⃣ Air Drying – The filtered liquid is dried to prepare for solvent-based extraction.

5️⃣ Extraction – The dried material undergoes extraction using N-ethane to isolate CoQ10 from the biomass.

6️⃣ Silica Gel Chromatography – Further purification using N-ethane and ethyl acetate, ensuring high-purity Coenzyme Q10.

7️⃣ Crystallization – The purified extract is crystallized using ethanol, forming high-purity CoQ10 powder.

8️⃣ Drying & Sieving – The crystallized Coenzyme Q10 is dried and sieved to achieve the desired particle size.

9️⃣ Packaging – The final CoQ10 powder is packed in a D Grade Clean Area, ensuring quality and stability, followed by inner and outer packaging before distribution.

🔹 Final Product: High-Purity Coenzyme Q10 Powder (Oil-Soluble or Water-Soluble, depending on formulation). 🚀✨

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9. Why Choose Chibio Biotech for Coenzyme Q10?

🌱 Premium Quality & High Purity – Coenzyme Q10 (98%, 10%, 20%) with strict quality control.

🔬 Highly Bioavailable Formulations – Offers both oil-soluble and water-soluble solutions.

🌍 ISO & Food-Grade Certified – Manufactured in ISO, and HACCP-compliant facilities.

📦 Bulk Supply & Custom Packaging – Available in 1kg, 5kg, 10kg, and 25kg drums.

📞 Reliable Global Distribution & Customer Support – Fast shipping and professional service.

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10. Looking for Premium Coenzyme Q10 for Your Supplements, Skincare, or Functional Foods?

📩 Email: sales@chibiotech.com
📞 Phone: +86 (0)532 66983270
🌍 Website: www.chibiotech.com

✅ Enhance your formulations with Chibio Biotech’s Coenzyme Q10 – The Ultimate Antioxidant for Health & Longevity! 🚀✨