Alpha arbutine

Alpha arbutine

Additional information

Product Name

Alpha-Arbutin
Synonyms: 4-Hydroxyphenyl-α-D-glucopyranoside

CAS Number

84380-01-8

Chemical Formula

C₁₂H₁₆O₇

Molecular Weight

272.26 g/mol

Appearance

White fine powder

Source

Enzymatic synthesis using hydroquinone and glucose

Solubility

Water soluble

Main Benefits

Superior Skin Brightening & Whitening, Safe & Non-Irritating, Fast & Long-Lasting Effects, Highly Stable & Water-Soluble, Works Well with Other Actives, Ideal for Sensitive Skin

Main Applicaitons

Skincare & Cosmetics, Dermatological & Pharmaceutical Use, Functional Personal Care Products

Product Details

Alpha-Arbutin – High-Performance Skin Brightening & Whitening Ingredient

 

 

Superior-Grade Alpha-Arbutin (≥99.5%) for Cosmetic & Skincare Applications


1. Introduction to Alpha-Arbutin

Alpha-Arbutin is a highly effective skin-lightening ingredient derived from hydroquinone-β-D-glucopyranoside, known for its powerful melanin-inhibiting properties. It is widely used in cosmetics, skincare, and dermatological formulations to reduce hyperpigmentation, dark spots, and skin discoloration.

At Chibio Biotech, we offer high-purity Alpha-Arbutin (≥99.5%), ensuring superior stability, safety, and efficacy for premium skin-brightening applications.


2. Source & Basic Information

Alpha-Arbutin is not a direct plant extract but a biosynthetic compound derived from natural sources. It is typically produced through enzymatic synthesis using hydroquinone and glucose, resulting in a high-purity, stable, and skin-safe whitening ingredient.

Sources of Alpha-Arbutin:

🌿 Originally Found in Plants – Naturally present in small amounts in certain plants, including:

  • Bearberry (Arctostaphylos uva-ursi)
  • Mulberry (Morus alba)
  • Blueberry (Vaccinium spp.)
  • Cranberry (Vaccinium macrocarpon)
  • Pear skins and wheat

⚗️ Commercial Production – Most Alpha-Arbutin available for cosmetics and skincare is produced via enzymatic synthesis. This method ensures:
High purity (≥99.5%)
Better stability compared to plant-extracted arbutin
Greater efficacy in melanin inhibition
No hydroquinone contamination (safe for long-term use)

Unlike Beta-Arbutin, which is often extracted from plants, Alpha-Arbutin is synthesized for superior bioavailability and effectiveness in skin-lightening applications. 🚀✨

  • Product Name: Alpha-Arbutin
  • Synonyms: 4-Hydroxyphenyl-α-D-glucopyranoside
  • CAS Number: 84380-01-8
  • Chemical Formula: C₁₂H₁₆O₇
  • Molecular Weight: 272.26 g/mol
  • Appearance: White fine powder
  • Odor & Taste: Characteristic, neutral

3. Product Specifications

Component Alpha-Arbutin 
Assay (HPLC) ≥99.5%
Melting Point 203.0—207ºC
pH (1% Solution) 5.0 – 7.0
Specific Optical Rotation +174.0º—+186.0º
Hydroquinone ≤10.0 ppm
Loss on Drying ≤0.5%
Heavy Metals Pb ≤10 ppm, As ≤2.0 ppm, Hg ≤1.0 ppm, Cd ≤5.0 ppm
Microbial Quality TPC ≤300 cfu/g, Yeast & Mold ≤100 cfu/g, E. coli, Pseudomonas aeruginosa, Staphylococcus aureus – Negative
Shelf Life 24 months
Storage Store in a cool, dry place, away from direct sunlight

4. Solubility & Functional Properties

  • Water Solubility: Highly soluble, making it ideal for liquid and cream-based cosmetic formulations.
  • Ethanol & Methanol Solubility: Fully dissolves, enhancing compatibility in skincare formulations.
  • Oil Solubility: Insoluble, best for water-based or emulsified formulations.
  • pH Stability: Optimal at pH 5.0-7.0, ensuring long-term effectiveness in cosmetic products.

5. HOW DOES Alpha Arbutin WORK?

Alpha arbutin is frequently marketed as a safer alternative to hydroquinone (a popular skin-lightening ingredient that has been banned in Europe and Australia).

It has similar results in brightening skin but without the dangerous bleaching process. Instead, it reduces skin’s pigment production by suppressing the enzymes that stimulate melanin. This also slows down the process by which UV light causes pigmentation, so it both prevents and treats pigmentation issues.


6. Key Advantages & Benefits

Superior Skin Brightening & Whitening – Effectively inhibits tyrosinase activity, reducing melanin production and improving skin tone.
Safe & Non-Irritating – Unlike hydroquinone, Alpha-Arbutin is gentle on the skin, with minimal risk of irritation or cytotoxicity.
Fast & Long-Lasting Effects – Provides visible skin-lightening results with consistent use.
Highly Stable & Water-Soluble – Ensures easy formulation in serums, creams, and lotions.
Works Well with Other Actives – Enhances efficacy when combined with Vitamin C, Niacinamide, and Hyaluronic Acid.
Ideal for Sensitive Skin – Suitable for all skin types, including sensitive and acne-prone skin.


7. Applications of Alpha-Arbutin

A. Skincare & Cosmetics

🔹 Whitening & Brightening Creams – Effectively reduces dark spots, melasma, and hyperpigmentation.
🔹 Anti-Aging Serums – Helps even skin tone and reduces age spots.
🔹 Sunscreen & UV Protection – Works as an anti-photoaging agent, preventing UV-induced pigmentation.
🔹 Eye Creams & Spot Treatments – Targets dark circles and localized hyperpigmentation.
🔹 Facial Toners & Essences – Enhances radiance and skin clarity.

B. Dermatological & Pharmaceutical Use

🔹 Hyperpigmentation Treatments – Used in dermatologist-prescribed formulations for post-inflammatory hyperpigmentation (PIH) and acne scars.
🔹 Melasma & Freckle Treatments – Helps fade freckles and discoloration caused by hormonal imbalances.

C. Functional Personal Care Products

🔹 BB Creams & Foundations – Used in cosmetic formulations to promote an even skin tone.
🔹 Body Lotions & Hand Creams – Reduces dark patches, rough spots, and uneven pigmentation.
🔹 Intimate Area Brightening Products – Used for sensitive area whitening treatments.


8.Recommended Dosage of Alpha-Arbutin in Different Applications

Application Recommended Dosage (%) Usage Notes
Whitening & Brightening Creams 1.0 – 2.0% Enhances skin tone and reduces pigmentation. Best combined with Vitamin C and Niacinamide.
Anti-Aging Serums & Essences 0.5 – 2.0% Provides skin-brightening effects while reducing fine lines.
Sunscreen & UV Protection Products 0.5 – 1.5% Prevents UV-induced pigmentation. Works well with SPF formulations.
Dark Spot & Hyperpigmentation Treatments 2.0 – 3.0% Targets age spots, melasma, and post-inflammatory hyperpigmentation (PIH).
Eye Creams & Under-Eye Brighteners 0.2 – 0.5% Helps lighten dark circles while being gentle on delicate skin.
Body Lotions & Brightening Moisturizers 1.0 – 2.0% Used for all-over skin brightening and evening skin tone.
Facial Toners & Mists 0.2 – 1.0% Provides a mild brightening effect and prepares skin for further treatment.
Intimate Area Whitening Products 1.0 – 2.0% Commonly used in underarm, bikini, and sensitive area brightening formulas.
BB Creams, Foundations & Makeup 0.2 – 1.0% Lightens complexion over time while offering cosmetic coverage.
Medical-Grade Dermatological Treatments 3.0 – 5.0% Used in professional skin-lightening formulas under dermatological supervision.

Key Formulation Guidelines:

Water-Soluble – Best used in water-based formulations (serums, creams, lotions, gels).
Optimal pH Range – Works best at pH 5.0 – 7.0 for maximum stability and efficacy.
Synergistic Combinations – Works well with Vitamin C, Niacinamide, Kojic Acid, and Hyaluronic Acid for enhanced skin-brightening results.
UV Protection Recommended – Always combine with SPF in daytime skincare to prevent further pigmentation.

Using Alpha-Arbutin at the correct concentration ensures safe, effective, and visible results in cosmetic and dermatological applications. 🚀🌿

9. Why Use Alpha-Arbutin in Your Business?

If you experience post-blemish redness, age spots, or acne scars then alpha-arbutin is very effective at treating these kinds of pigmentation. It also helps to even out skin tone and reduce overall redness. If you have sensitive skin, then it’s worth giving alpha-arbutin a try since it’s known for being gentler than other skin brighteners like retinol and glycolic acid.

💎 Clinically Proven Skin Whitening IngredientMore potent and stable than Beta-Arbutin, ensuring fast and long-lasting skin brightening.

🔬 Scientifically Backed & Safe for Long-Term Use – Unlike hydroquinone, Alpha-Arbutin has no known toxicity, making it a safe alternative.

☀️ Photostable & Effective Against UV-Induced Damage – Protects skin against sun damage and pigmentation.

🌿 Compatible with Clean & Natural Formulations – Perfect for clean-label, eco-friendly, and non-toxic skincare brands.

🌍 Vegan & Cruelty-Free – Derived from plant-based sources, making it ideal for vegan and ethical skincare brands.

🚀 Growing Consumer Demand for Skin Brightening Products – The global skin-whitening and anti-aging market is expanding rapidly, creating huge business opportunities.


10. Why Choose Chibio Biotech for Alpha-Arbutin?

🌱 Premium Quality & High Purity (≥99.5%) – Chibio Biotech guarantees high stability and effectiveness in cosmetic formulations.

🌍 Sustainably Sourced & Eco-Friendly – Our Alpha-Arbutin is produced under strict quality control for maximum efficacy and safety.

🔬 ISO & Cosmetic-Grade Certification – Manufactured in ISO-certified, ISO-compliant facilities, ensuring consistency and safety.

📦 Bulk Supply & Custom Packaging – Available in 1kg, 10kg, and 25kg bulk sizes to meet business needs.

🏆 Trusted Supplier for Skincare Brands – Chibio Biotech is a reliable partner for leading cosmetic and dermatological brands worldwide.

📞 Reliable Global Distribution & Customer Support – We provide fast shipping, responsive service, and international logistics support.


11. Get in Touch – Inquiry Now!

📩 Email: sales@chibiotech.com
📞 Phone: +86 (0)532 66983270
🌍 Website: www.chibiotech.com

By choosing Chibio Biotech Alpha-Arbutin, you ensure high-quality, scientifically backed, and market-driven skin-brightening solutions for cosmetic and dermatological applications. 🚀

Get in touch with us to boost your business

Headquarter

Block B, Vanke Center, No.2 Heilongjiang South Road, Shibei District, Qingdao City, China 266033

Phone

+86 (0)532 66983270

Cellphone / WhatsApp / WeChat

+86 156 6577 2296
+86 133 8100 5417

sales@chibiotech.com

Let's get in touch to start 100% natural plant-based life NOW!