🧬 Urolithin A

Advanced Anti-Aging Ingredient for Longevity Nutrition & Next-Generation Skincare

Urolithin A is a bioactive metabolite derived from ellagitannins (found in pomegranate and other fruits), widely recognized for its ability to stimulate mitophagy (mitochondrial renewal).

Originally developed for nutraceutical and longevity applications, Urolithin A is now emerging as a next-generation cosmetic active ingredient, with major global companies such as L’Oréal exploring its application in anti-aging skincare.

Chibio Biotech supplies high-purity Urolithin A ≥99%, suitable for both dietary supplement and cosmetic formulations, supporting cellular energy, skin rejuvenation, and healthy aging.

📌 1. Basic Information

Item	Details
Product Name	Urolithin A
CAS No.	1143-70-0
Appearance	Light yellow powder
Purity	≥99%
Origin	Natural metabolite (ellagitannin-derived)
Grade	Nutraceutical Grade
Shelf Life	24 months

Product complies with COA specifications and quality standards  .

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⚗️ 2. COA Specifications

Parameter	Specification	Result
Purity (HPLC)	≥99.0%	99.2%
Assay (dry basis)	≥98.0%	98.7%
Appearance	Light yellow powder	Conforms
Identification (HPLC / NMR)	Corresponds to reference	Conforms
Water Content	≤0.5%	0.33%
Residue on Ignition	≤0.5%	0.25%
Particle Size	≥95% pass 40 mesh	Conforms
Bulk Density (Loose)	≥0.2 g/ml	0.40 g/ml
Heavy Metals	≤10 mg/kg	Conforms
Lead	≤0.5 mg/kg	Conforms
Arsenic	≤1.0 mg/kg	Conforms
Cadmium	≤1.0 mg/kg	Conforms
Mercury	≤0.1 mg/kg	Conforms
Total Plate Count	≤1000 CFU/g	Conforms
Yeast & Mold	≤100 CFU/g	Conforms
E. coli	Negative	Conforms
Salmonella	Negative	Conforms

Product meets high purity and safety requirements  .

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💧 3. Key Product Characteristics

✔ High purity ≥99%

✔ Non-GMO, non-animal origin

✔ Supports mitochondrial function

✔ Excellent stability for formulations

✔ Suitable for capsules, tablets, and powders

✔ Premium longevity ingredient

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🧪 4. Functional Benefits

🔋 Mitochondrial Health Support

Activates mitophagy to remove damaged mitochondria and support cellular energy production.

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⏳ Anti-Aging Support

Promotes healthy aging by improving cellular function and energy metabolism.

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💪 Muscle Health & Endurance

Supports muscle function and may improve physical performance.

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🧠 Cognitive Support

Improves cellular energy metabolism, which may benefit brain health.

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🛡 Cellular Protection

Helps maintain cellular integrity through improved mitochondrial turnover.

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⚡ Energy Metabolism

Supports ATP production and overall metabolic efficiency.

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🏭 5.1 Applications

💊 Dietary Supplements

Used in:

• anti-aging supplements

• longevity formulas

• mitochondrial health products

Dosage:

250 – 500 mg/day

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🧴 Skincare & Cosmetics (NEW FOCUS)

Applications include:

• anti-aging creams

• serums

• eye care products

• dermal repair formulations

Suggested usage:

0.05% – 0.5%

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💪 Sports Nutrition

• endurance products

• recovery formulations

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🥤 Functional Foods & Beverages

• anti-aging drinks

• wellness nutrition

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5.2 Cosmetic & Skincare Functions

✨ Cellular Skin Rejuvenation

Urolithin A activates mitochondrial renewal in skin cells, helping improve skin vitality and regeneration.

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⏳ Anti-Aging & Wrinkle Reduction

Supports reduction of visible aging signs by improving cellular energy and turnover.

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🔬 Dermal Energy Boost

Enhances energy metabolism in skin cells, leading to:

• improved skin firmness

• better elasticity

• healthier skin appearance

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🛡 Anti-Oxidative & Protective Effect

Helps protect skin from oxidative stress and environmental damage.

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🌿 Skin Barrier Support

Improves skin resilience and barrier function, supporting hydration and repair.

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🌍 Market Trend Insight

• Urolithin A is considered a “next-generation cosmetic active”

• Global brands (e.g., L’Oréal) are exploring mitochondrial skincare

• Fits perfectly into clean beauty + biotech skincare trends

👉 This positions Urolithin A as a high-end differentiating ingredient in cosmetics.

⚙️ 6. Production Process Overview

Raw Material Selection

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Chemical Synthesis / Biotransformation

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Purification

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Crystallization

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Drying

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Quality Testing

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Packaging

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🔍 7. Comparison: Urolithin A vs NMN vs Resveratrol

Feature	Urolithin A	NMN	Resveratrol
Mechanism	Mitophagy activation	NAD+ booster	Antioxidant
Target	Mitochondria	Cellular metabolism	Oxidative stress
Bioavailability	High	Moderate	Low
Anti-aging approach	Cellular renewal	Energy metabolism	Free radical protection
Market trend	Rapid growth	Mature	Traditional

Key Insight

• Urolithin A = next-generation longevity ingredient

• Focuses on mitochondrial renewal, not just antioxidant activity

• Strong positioning in premium anti-aging products

Comparison: Urolithin A vs Traditional Anti-Aging Ingredients

Feature	Urolithin A	Resveratrol	CoQ10
Mechanism	Mitophagy	Antioxidant	Energy cofactor
Target	Mitochondria	Free radicals	Energy production
Innovation Level	Next-gen	Traditional	Mature
Cosmetic Trend	Rapid growth	Stable	Stable

Key Insight

• Urolithin A = next-generation anti-aging mechanism

• Focuses on cellular renewal, not just protection

• Strong appeal in premium skincare and biotech beauty

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📦 8. Packaging & Storage

Standard packaging:

• 5 kg / 20 kg / 25 kg fiber drum

Storage conditions:

• Store in cool, dry, ventilated place

• Avoid light and contamination

Shelf life:

24 months under proper storage  .

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🏆 9. Why Choose Chibio Biotech?

🌍 International Certifications

Chibio Biotech holds:

• ISO 22000

• HALAL Certification

• KOSHER Certification

• US FDA Food Facility Registration

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🔬 Strict Quality Control

• ≥99% purity assurance

• Heavy metal control

• Microbiological safety

• Batch traceability

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🚚 Reliable Global Supply

• Stable production capacity

• Consistent quality

• Export experience worldwide

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📊 10. Summary

Chibio’s Urolithin A is a next-generation bioactive ingredient with dual functionality in:

• Longevity nutrition

• Advanced anti-aging skincare

With growing adoption by leading global cosmetic brands, it represents a high-value, future-oriented ingredient for both nutraceutical and beauty markets.

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📩 Looking for premium Urolithin A for supplements or skincare formulations?

📧 Email: sales@chibiotech.com

📞 Phone: +86 (0)532 66983270

🌍 Website: www.chibiotech.com

✅ Chibio Biotech – Next-Generation Ingredients for Longevity & Beauty Innovation.

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