1. Product Introduction

Microcrystalline Cellulose (MCC) is a purified, partially depolymerized cellulose widely used as an excipient in pharmaceutical, nutraceutical, and food industries. It is valued for its excellent binding, compressibility, and flow properties, making it ideal for tablet manufacturing and powder formulations.

Chibio Biotech supplies USP-grade Microcrystalline Cellulose with controlled particle size distribution, low moisture content, and strict microbial limits to ensure consistent performance in industrial formulations.

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🧬 2. Basic Information

Item	Details
Product Name	Microcrystalline Cellulose
Abbreviation	MCC
CAS No.	9004-34-6
Standard	USP40–NF35
Appearance	White to off-white powder
Shelf Life	24 months
Storage	Cool, dry place in sealed packaging

⚗️ 3. Technical Specifications (COA Summary)

Parameter	Specification	Result
Appearance	White to off-white powder	Conforms
Degree of Polymerization	≤350	243
pH	5.0 – 7.5	5.9
Loss on Drying	≤7.0%	4.2%
Residue on Ignition	≤0.1%	0.08%
Water Soluble Content	≤0.25%	0.13%
Ether Soluble Content	≤0.05%	0.02%
Conductivity	≤75 μS/cm	14.9 μS/cm
Bulk Density	0.25–0.4 g/cm³	Conforms
Particle Size	40–60 µm	51 µm

🧪 4. Microbiological Specifications

arameter	Specification	Result
Total Plate Count	≤1000 CFU/g	30 CFU/g
Yeast & Mold	≤100 CFU/g	30 CFU/g
E. coli	Negative	Negative
Salmonella	Negative	Negative

These results confirm the product meets strict pharmaceutical-grade microbial safety requirements.

💧 5. Solubility & Functional Characteristics

• Insoluble in water

• Forms stable suspensions in aqueous systems

• Excellent compressibility for tablet manufacturing

• High surface area improves binding properties

• Chemically inert and physiologically inert

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🧬 6. Functional Benefits

1. Tablet Binder – improves mechanical strength of tablets

2. Filler / Diluent – increases bulk in tablet formulations

3. Disintegrant – promotes rapid tablet disintegration

4. Stabilizer – stabilizes emulsions and suspensions

5. Fat Replacement (Food Industry) – reduces calorie density

6. Texture Enhancer – improves mouthfeel in food products

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🧴 7. Applications (Functional Role & Dosage Guidance)

💊 Pharmaceutical Tablets

Function

• Binder for direct compression

• Improves tablet hardness and stability

• Enhances powder flowability

Typical Usage

• 10–60% of tablet formulation depending on formulation design.

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💊 Nutraceutical Supplements

Function

• Capsule filler

• Tablet excipient

• Improves powder compressibility

Typical Dosage

• 20–80% depending on active ingredient concentration.

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🍔 Food Applications

Function

• Low-calorie bulking agent

• Fat replacer in processed foods

• Texture stabilizer in sauces and dressings

Typical Inclusion

• 0.5–3% in food formulations.

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🧴 Cosmetic Applications

Function

• Oil absorbent

• Texture modifier

• Stabilizer for creams and lotions

Typical Inclusion

• 1–5% depending on formulation.

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⚙️ 8. Production Process Overview

Natural Cellulose Source

⬇

Alkaline Purification

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Acid Hydrolysis

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Neutralization

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Drying

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Milling

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Particle Size Control

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USP Quality Testing

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Packaging

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🏆 9. Why Choose Chibio Biotech?

International Certifications

Chibio Biotech has obtained:

• ISO 22000 Certification

• HALAL Certification

• KOSHER Certification

• US FDA Food Facility Registration

These certifications ensure global regulatory compliance and customer confidence.

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Strict Quality Control

• USP40-NF35 compliance 

• Low heavy metal content

• Controlled particle size distribution

• Microbial safety verification

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Stable Production Capacity

• Large-scale manufacturing capability (10,000 kg batch) 

• Consistent batch quality and traceability

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Flexible Packaging Options

• Inner food-grade plastic bag

• Outer triple-layer kraft paper bag 

• Customized packaging available

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11. Summary

Chibio’s Microcrystalline Cellulose (MCC) provides a high-performance excipient for pharmaceutical, nutraceutical, food, and cosmetic formulations. With excellent compressibility, binding capability, and stability, it ensures reliable product performance across multiple industries.

📩 Looking for high-quality USP-grade Microcrystalline Cellulose for your formulations?

📧 Email: sales@chibiotech.com

📞 Phone: +86 (0)532 66983270

🌍 Website: www.chibiotech.com

✅ Chibio Biotech – Reliable Functional Excipients for Modern Formulation Science. 🌿✨