Product Name | L-Se-Methylselenocysteine |
---|---|
CAS Number | 1464-43-5 |
Appearance | White powder or granule, garlic-like odor |
Key Properties | High bioavailability, low toxicity, and potent antioxidative and anti-inflammatory properties |
Main Benefits | ✅ Superior Selenium Bioavailability |
Main Applications | 1. Nutraceuticals & Dietary Supplements |
Chinese Name: L-硒-甲基硒代半胱氨酸
Grade: Food Grade
CAS Number: 1464-43-5
Chemical Formula: C4H9NO2Se | Molecular Weight: 184.08 g/mol
Form: White powder or granules with garlic-like odor
L-Se-Methylselenocysteine (L-SeMC) is a naturally occurring organic selenium compound found in Allium (garlic, onion) and Brassica (broccoli, cabbage) vegetables. It is widely recognized as the most effective and safest form of selenium supplementation, offering high bioavailability, low toxicity, and potent antioxidative and anti-inflammatory properties.
L-Se-Methylselenocysteine is a natural selenium compound found in plants like garlic and broccoli. Unlike other forms (e.g., selenite, selenomethionine), L-SeMC provides directly usable selenium for cellular defense, with high bioavailability, antioxidant synergy, and excellent safety.
Item | Specification | Result |
---|---|---|
Appearance | White powder or granule, garlic-like odor | Complies |
L-SeMC Content | ≥96% | 99.3% |
Specific Rotation (aqueous) | – | -13 |
Loss on Drying | ≤1.0% | 0.6% |
pH (1% solution) | 4.5 – 6.5 | 5.5 |
Total Arsenic (As) | ≤2.0 mg/kg | Not detected |
Lead (Pb) | ≤2.0 mg/kg | Not detected |
Microbial Limit | Meets GB1903.12 food safety standard | Passed |
✅ Complies with GB1903.12 national food safety standards
Water: Freely soluble
Ethanol: Slightly soluble
Oil: Insoluble
✅ Superior Selenium Bioavailability – >90% absorption vs. inorganic selenium
🛡 Antioxidant & Detoxification – Neutralizes free radicals and supports glutathione activity
🧬 DNA Repair & Anti-cancer Support – Promotes apoptosis in abnormal cells
💊 Thyroid Function & Hormonal Balance – Selenium is essential for T3–T4 conversion
🧠 Neuroprotection & Cognitive Support – Linked to reduced risk of neurodegenerative decline
❤️ Cardiovascular Protection – Reduces inflammatory markers and oxidative stress
💊 Capsules & tablets for:
Immune health
Thyroid support
Detoxification formulas
✅ Suggested dosage: 50–200 µg selenium/day
⚠ L-SeMC yields approx. 400–500 µg selenium per mg.
🥤 Added to:
Fortified juices or water-soluble sachets
Daily wellness blends (with zinc, vitamins C & E)
✅ Dosage: 50–100 µg selenium/serving
✅ Water-soluble, neutral taste in small amounts
🌿 Topical or oral use for:
Antioxidant skin care (with glutathione, CoQ10)
Scalp/hair vitality products
✅ Typical usage: 0.01–0.1% in creams or lotions
🐕🐓🐄 Used in:
Poultry & swine feed premixes
Pet supplements for antioxidant & immune protection
✅ Dosage: 0.2–0.5 mg selenium/kg feed (adjust based on selenium yield)
📚 In clinical study pipelines for:
Anti-tumor adjuvant therapy (chemoprevention)
Neuroprotective dietary support
✅ Delivered in clinical formulas (under research)
Application | Purpose | Suggested Dosage |
---|---|---|
Nutraceuticals | Capsules, tablets for antioxidant and detox formulas | 50–200 µg/day selenium equivalent |
Functional Foods | Fortified foods, beverages | 20–100 µg/serving |
Cosmetics (Emerging) | Anti-aging skin care, scalp health | 0.01–0.1% (water-soluble formats) |
Animal Nutrition | Organic selenium for livestock, poultry | 0.2–0.5 mg/kg of feed |
📌 1 mg L-SeMC contains approx. 400–500 µg selenium, adjust dosing carefully.
Selenium Type | Absorption | Toxicity | Stability | Formulation Flexibility |
---|---|---|---|---|
L-SeMC | ★★★★★ | Low | Stable in powder form | Excellent (capsules, foods) |
Sodium Selenite | ★★ | High | Less stable | Limited use |
Selenomethionine | ★★★★ | Moderate | Moderate | Common in supplements |
Yeast Selenium | ★★★ | Moderate | Variable | Needs organic Se validation |
🧠 L-SeMC is regarded as the most stable and bioavailable selenium form for functional food and nutraceutical applications.
Packing: 100galuminum foil bags; 25kg/drum
Shelf Life: 24 months in sealed container under cool, dry, dark conditions
Raw Material Selection
→ High-purity precursors with selenium enrichment
Synthesis Reaction
→ Controlled reaction to form L-Se-methylselenocysteine
Purification & Crystallization
→ Remove by-products, achieve ≥99% purity
Drying & Granulation
→ Spray or vacuum drying to produce stable powder
Screening & QC Testing
→ Mesh sizing, HPLC assay, microbial & heavy metal testing
Packaging
→ Aluminum foil or drum; nitrogen protection optional
🔬 Scientifically Superior Organic Selenium – High purity (99.3%), low heavy metals, safe and effective
📈 Market Demand for Antioxidant and Immunity Solutions – Especially in post-pandemic immune health, detox, and anti-aging sectors
🧪 Multi-Industry Use – Ideal for dietary supplements, functional foods, beauty-from-within, and even pet nutrition
🌍 Clean Label Ready – Vegan, non-GMO, allergen-free, and water-soluble
💼 Premium Positioning – Allows higher pricing, better claims, and stronger scientific backing than basic selenium forms
Feature | Value |
---|---|
✅ High absorption rate | Over 90% selenium bioavailability |
✅ Safety | Low toxicity, even at higher concentrations |
✅ Efficacy | Directly incorporated into antioxidant systems (e.g., GPx enzymes) |
✅ Stability | Excellent shelf stability, no need for refrigeration |
✅ Label-Friendly | Clean label, organic selenium, vegan, gluten-free |
✅ Differentiation | Premium position compared to selenomethionine or selenite |
≥99.3% Purity L-SeMC based on validated HPLC methods
Strict compliance with GB1903.12, USP, and food-grade safety standards
Tested for heavy metals, microbial load, and stability — every batch with COA, MSDS, and TDS
Specialized in high-activity, bioavailable ingredients such as L-SeMC, NMN, Beta Glucan, etc.
Ability to explain and support health claims through scientific data
Custom formulation support: blends with vitamin E, glutathione, or selenium yeast if needed
Food-grade, vegan, non-GMO, and non-toxic formulations
Transparent sourcing and processing – free from unwanted additives, preservatives, or artificial carriers
Meets international regulations (EU, USA, APAC) for nutritional and functional foods
GMP-certified production lines
Clean-room environments, proprietary drying and crystallization processes
Custom packaging available (1g–25kg), nitrogen-sealed upon request
Consistent inventory and reliable bulk supply capacity
Professional logistics handling for sensitive bioactive compounds
Fast response for sampling, documentation, and formulation consultation
Over 200+ specialty ingredients across:
Immunity & detox
Brain & longevity
Functional beauty & active aging
Always updated with the latest science and market trends
📩 Interested in premium selenium innovation for your product lines?
📧 Email: sales@chibiotech.com | 🌐 www.chibiotech.com | 📞 +86 532 66983270
✅ Chibio Biotech – Precision Ingredients for Functional Health Solutions
Block B, Vanke Center, No.2 Heilongjiang South Road, Shibei District, Qingdao City, China 266033
+86 (0)532 66983270
+86 156 6577 2296
+86 133 8100 5417