1.What is NMN?
NMN (Nicotinamide mononucleotide): The full name is "β-nicotinamide mononucleotide", which is a naturally occurring biologically active nucleotide. There are two irregular forms of NMN, α and β; β isomer is the active form of NMN with a molecular weight of 334.221 g/mol. Because nicotinamide belongs to vitamin B3, NMN belongs to the category of vitamin B derivatives. It is widely involved in many biochemical reactions of the human body and is closely related to immunity and metabolism.
The substances inherent in the human body are also rich in some fruits and vegetables. In the human body, NMN is the most direct precursor of NAD+, and its function is manifested through NAD+. NAD+ is also called Coenzyme I, and its full name is nicotinamide adenine dinucleotide. It exists in every cell and participates in thousands of reactions. In a variety of cellular metabolic reactions, nicotinamide adenine dinucleotide (NAD) molecules play an important role and are an important support for cells to maintain vitality.
The decline of NAD in the aging process is considered to be the main cause of diseases and disability, such as hearing and vision loss, cognitive and motor dysfunction, immune deficiency, arthritis, metabolic disorders and cardiovascular diseases caused by dysregulation of autoimmune inflammation. Therefore, supplementation of NMN increases the NAD+ content in the body, thereby delaying, improving, and preventing various phenotypes related to aging, or age-induced metabolic disorders, senile diseases, and so on.
NMN is the abbreviation of β-nicotinamide mononucleotide. It naturally exists in living cells and is the precursor of Coenzyme 1 NAD+ (nicotinamide adenine dinucleotide). It can extend the lifespan appropriately. The real anti-aging effect is an important energy metabolite called nicotinamide adenine dinucleotide (NAD+).
With age, the decrease of NAD+ level leads to the decline of DNA repair ability, accumulation of DNA damage, and drive the aging process. NAD+ participates in cellular respiration in cells and promotes energy metabolism (such as oxidation of glucose, fat, and amino acids). NAD+ is not only a coenzyme for hundreds of redox reactions in living cells, it also acts as a substrate to regulate cell survival, cell apoptosis, DNA repair, immune response, circadian rhythm and other physiological functions.
NMN is a nutrient substance that is converted into NAD+ in the cells. It is classified as a brand-new vitamin B3, and surpasses the efficacy of ordinary vitamins. It is considered as a supplement for preventing aging and restoring youth. NMN itself is a substance contained in the human body, present in breast milk and food, such as edamame, broccoli, cucumber, cabbage, avocado, tomato, etc., but the content is very small (0.25-1.88 mg per 100 grams). Raw beef and shrimp also contain very small amounts of NMN (0.06-0.42 mg per 100 grams). Therefore, if you want to improve NMN, you must directly supplement it from the outside world.
NMN is a substance naturally produced in humans and organisms. From the point of view that breast milk contains NMN, it can be said that it is one of the nutrients that humans first ingest after birth. Yellow-green vegetables also contain NMN, so unlike medicines, NMN is a natural source of food and is safe. However, the possibility of individual effects like food allergies cannot be ruled out.
2.Specification Of Alginate Oligosaccharide
3.Benefits & Applications of NMN
Harvard genetics professor David Sinclair proposed that NMN has the effect of reversing aging: by maintaining sufficient NAD+ in the cell, it can maintain the self-repairing ability of DNA, so that the DNA damage caused by aging can be effectively repaired, thereby Inhibit aging. The raw material of NMN is the precursor of NAD+. Taking NMN can increase the level of NAD+ in the body.
Authoritative international journals such as "CELL", "NATURE" and "SCIENCE" have confirmed the anti-aging effect of NMN on the body from multiple angles. In 2016, an experimental study by Professor David Sinclair found that mice equivalent to 70 years old of humans returned to their 20-year-old state after taking NMN for a week, and their lifespan was extended by 20%. The effect of NMN has been confirmed in this endless series of related theories and numerous experiments by many scientists.
1.The elderly, used to help improve various senile diseases;
2.Middle-aged people, resolve or alleviate various sub-health problems, such as chronic fatigue, poor sleep, and decreased vision;
3.Those who stay up late will speed up the body's recovery;
4.Candidates should improve their ability to resist stress and keep their heads clear;
5.Those with higher radiation doses, such as radiologists, nurses, and air crews, improve the ability to repair genes damaged by radiation;
6.For cancer patients, help patients repair their genes after radiotherapy and chemotherapy, improve immunity and speed up physical recovery;
7.Bodybuilders, accelerate muscle growth;
8.Athletes, improve energy level and reaction speed;
9.Drinkers, improve the ability to hangover, protect the liver, and repair genes that are toxic to acetaldehyde;
10.Depressed people, increase dopamine levels, improve mood, increase blood supply to the brain, and alleviate brain decline caused by depression;
11.Middle-aged and elderly women improve skin health and delay skin aging.
Since the discovery of NAD+ in 1906, the molecule has attracted the attention of scientists because of its abundance in the human body and its key role in the molecular pathways that maintain the functioning of the human body. In animal studies, increasing the level of NAD+ in the body has shown encouraging results in research fields such as metabolism and age-related diseases, and even shows some anti-aging properties. Age-related diseases such as diabetes, cardiovascular disease, neurodegeneration and general decline of the immune system.